Hypothesis Concerning Carbonic Anhydrase Treatment of Cystoid Macular Edema: Example With Epiretinal Membrane

Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome

“…This finding is similar to two previous studies that demonstrated the beneficial effect of CAIs in one patient with Enhanced S-cone syndrome in each study [6,7]. CAIs have been shown to be effective for the improvement of cystic macular changes in patients with other retinal diseases such as retinitis pigmentosa [8,9], uveitis [21], X-linked retinoschisis [10,22], and for patients with epiretinal membranes [23]. Improvement in our case included a marked decrease in central macular thickness on spectral-domain OCT exam and an increase in retinal sensitivity on microperimetry testing.…”

Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome

“…This finding is similar to two previous studies that demonstrated the beneficial effect of CAIs in one patient with Enhanced S-cone syndrome in each study [6,7]. CAIs have been shown to be effective for the improvement of cystic macular changes in patients with other retinal diseases such as retinitis pigmentosa [8,9], uveitis [21], X-linked retinoschisis [10,22], and for patients with epiretinal membranes [23]. Improvement in our case included a marked decrease in central macular thickness on spectral-domain OCT exam and an increase in retinal sensitivity on microperimetry testing.…”

The Efficacy of Acetazolamide on Visual Functions in a Patient With Choroid Metastasis of Breast Carcinoma

“…Acetazolamide has been used clinically for over a decade to lower intraocular pressure, and more recently has been shown to improve cystoid macular oedema from various aetiologies 4 . It is important to evaluate the effect of acetazolamide on the macular circulation of patients with macular oedema from other causes, such as retinitis pigmentosa, aphakia and uveitis, because the most beneficial effects of this drug have been reported in these patients 3,4 . Acetazolamide has caused an increase in both passive and unidirectional permeability.…”

Advancing Insights into Pediatric Macular Diseases: A Comprehensive Review

“…The proposed mechanism involves facilitating fluid transport out of the retina, reducing cystic space volume, and potentially promoting cellular adhesion [ 121 , 122 , 123 ]. This may be achieved through increased acidification of the subretinal space, which results in enhancing fluid movement to the choroid [ 124 , 125 ].…”

Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome

“…This finding is similar to two previous studies that demonstrated the beneficial effect of CAIs in one patient with Enhanced S-cone syndrome in each study [6,7]. CAIs have been shown to be effective for the improvement of cystic macular changes in patients with other retinal diseases such as retinitis pigmentosa [8,9], uveitis [21], X-linked retinoschisis [10,22], and for patients with epiretinal membranes [23]. Improvement in our case included a marked decrease in central macular thickness on spectral-domain OCT exam and an increase in retinal sensitivity on microperimetry testing.…”

The Efficacy of Acetazolamide on Visual Functions in a Patient With Choroid Metastasis of Breast Carcinoma

“…Acetazolamide has been used clinically for over a decade to lower intraocular pressure, and more recently has been shown to improve cystoid macular oedema from various aetiologies 4 . It is important to evaluate the effect of acetazolamide on the macular circulation of patients with macular oedema from other causes, such as retinitis pigmentosa, aphakia and uveitis, because the most beneficial effects of this drug have been reported in these patients 3,4 . Acetazolamide has caused an increase in both passive and unidirectional permeability.…”

Advancing Insights into Pediatric Macular Diseases: A Comprehensive Review

“…The proposed mechanism involves facilitating fluid transport out of the retina, reducing cystic space volume, and potentially promoting cellular adhesion [ 121 , 122 , 123 ]. This may be achieved through increased acidification of the subretinal space, which results in enhancing fluid movement to the choroid [ 124 , 125 ].…”

Efficacy of topical dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome

“…This finding is similar to two previous studies that demonstrated the beneficial effect of CAIs in one patient with Enhanced S-cone syndrome in each study [6,7]. CAIs have been shown to be effective for the improvement of cystic macular changes in patients with other retinal diseases such as retinitis pigmentosa [8,9], uveitis [21], X-linked retinoschisis [10,22], and for patients with epiretinal membranes [23]. Improvement in our case included a marked decrease in central macular thickness on spectral-domain OCT exam and an increase in retinal sensitivity on microperimetry testing.…”

The Efficacy of Acetazolamide on Visual Functions in a Patient With Choroid Metastasis of Breast Carcinoma

“…Acetazolamide has been used clinically for over a decade to lower intraocular pressure, and more recently has been shown to improve cystoid macular oedema from various aetiologies 4 . It is important to evaluate the effect of acetazolamide on the macular circulation of patients with macular oedema from other causes, such as retinitis pigmentosa, aphakia and uveitis, because the most beneficial effects of this drug have been reported in these patients 3,4 . Acetazolamide has caused an increase in both passive and unidirectional permeability.…”

Advancing Insights into Pediatric Macular Diseases: A Comprehensive Review

“…The proposed mechanism involves facilitating fluid transport out of the retina, reducing cystic space volume, and potentially promoting cellular adhesion [ 121 , 122 , 123 ]. This may be achieved through increased acidification of the subretinal space, which results in enhancing fluid movement to the choroid [ 124 , 125 ].…”