Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

1
27
0

Year Published

2016
2016
2016
2016

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 19 publications
(28 citation statements)
references
References 0 publications
1
27
0
Order By: Relevance
“…Pazienza et al, showed that macroH2A1.1, which is a variant of histone H2A, binds O-acetyl ADP ribose (a small metabolite produced from the reaction catalyzed by Sirt1) with high affinity and protects hepatocytes against lipid accumulation, resulting in the suppression of non-alcoholic steatohepatitis [19]. Therefore, the activation of Sirt1 can exert many physiological effects, including reduced apoptosis, enhanced mitochondrial biogenesis, the inhibition of inflammation, the regulation of glucose and lipid metabolism, the regulation of the circadian rhythm, the induction of autophagy and adaptations to cellular stresses such as hypoxia, endoplasmic reticulum (ER) stress and oxidative stress [11, 12, 20]. …”
Section: Introductionmentioning
confidence: 99%
“…Pazienza et al, showed that macroH2A1.1, which is a variant of histone H2A, binds O-acetyl ADP ribose (a small metabolite produced from the reaction catalyzed by Sirt1) with high affinity and protects hepatocytes against lipid accumulation, resulting in the suppression of non-alcoholic steatohepatitis [19]. Therefore, the activation of Sirt1 can exert many physiological effects, including reduced apoptosis, enhanced mitochondrial biogenesis, the inhibition of inflammation, the regulation of glucose and lipid metabolism, the regulation of the circadian rhythm, the induction of autophagy and adaptations to cellular stresses such as hypoxia, endoplasmic reticulum (ER) stress and oxidative stress [11, 12, 20]. …”
Section: Introductionmentioning
confidence: 99%
“…2A; p < 10 −4 ), with SMPs grown in FGF2 having the greatest average proliferation rate compared to SMPs grown without exogenously added growth factors (Fig. 2B; p < 0.05, two way repeated measures ANOVA with Tukey post-hoc testing); effects with other growth factors were not significantly better than proliferation rates without added growth factors, despite contrary observations with mouse SMPs 1720 (Fig. 2).…”
Section: Resultsmentioning
confidence: 84%
“…Based on previous literature, FGF2, 17 FGF6, 17 FGF19, 17 HGF, 18 IGF1, 19 and oxytocin 20 were added individually, in combination, or not at all to growth medium. Again SMPs were cultured on 11 kPa PA hydrogels with collagen IV and laminin-111 as well as on glass.…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations