BMJ volume 295, issue 6591, P161-163 1987 DOI: 10.1136/bmj.295.6591.161 View full text
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C J Mathias, D F da Costa, P Fosbraey, N J Christensen, R Bannister

Abstract: AbstractThe haemodynamic responses to intravenous insulin (0-15 units/ kg) were measured in five patients with chronic autonomic failure who were not receiving drug treatment. After the administration of insulin supine blood pressure fell steadily, with a substantial reduction even before the onset of hypoglycaemia. None of the patients showed the usual range of neuroglycopenic symptoms, but they all became drowsy, with increasing sedation as the blood glucose concentration fell. In four other patients with a…

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