Hypolipemic and antioxidant activities from Tamarindus indica L. pulp fruit extract in hypercholesterolemic hamsters

Martinello, Flávia; Soares, S.M.; Franco, Juliana Bertoldi; Santos, Antonio Cardoso dos; Sugohara, Atushi; Garcia, Sérgio Britto; Curti, Carlos; Uyemura, Sérgio Akira

doi:10.1016/j.fct.2005.10.011

Cited by 167 publications

(137 citation statements)

References 49 publications

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“…Tamarind pulp also claims some medical uses and is regarded as a digestive, carminative, laxative, expectorant and blood tonic [11]. The pulp has been found to possess hypolipidemic activity [14]. Tamarind intake helps in delaying the progression of flourisis in humans by enhancing the urinary excretion of fluorine [15].…”

Section: Uses Of Tamarind Pulpmentioning

confidence: 99%

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2017

MOJFPT

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Section: Uses Of Tamarind Pulpmentioning

confidence: 99%

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2017

MOJFPT

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“…Aqueous extract of S. rebaudiana [12], M. koenigii [13], T. indica [14], hydroalcoholic extract of G. sylvestre [15,16], A. sativum [17], and M. charantia [18] were reported as good antidiabetic agents. Hence, these extracts were used for preparing microencapsulated formulations F1 and F2 for the treatment of diabetes.…”

Section: Preparation Of Formulationmentioning

confidence: 99%

Development and validation of HPTLC method for estimation of gymnemic acid in microencapsulated antidiabetic polyherbal formulations

Patil

Nirmal

Chavan

2013

Acta Chromatographica

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Summary. Gymnemic acid (GA) is one of the phytoconstituents present in Gymnema sylvestre. Estimation of GA was carried out first time from microencapsulated polyherbal formulation. Microencapsulated polyherbal formulations (F1 and F2) contain various plant extracts; hence, proper resolution of GA peak in high-performance thin-layer liquid chromatography (HPTLC) analysis of F1 and F2 is the problem. Hence, HPTLC analysis method for F1 and F2 is developed and validated for quantitative determination of GA. HPTLC analysis of F1 and F2 was carried out using TLC aluminum plates precoated with silica gel 60F 254 eluted with chloroform-methanol-water (6.5 mL + 4.5 mL + 1.0 mL), and densitometric analysis was carried out at 580 nm. Complete validation was performed using standard methods. This HPTLC method was found to be reproducible, accurate, and can detect GA at microgram level. The new optimized mobile phase gave good resolution of GA peak for its proper quantification in microencapsulated polyherbal formulation.

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“…Tamarindus indica is traditionally very important herb having many important activities like antidiabetic 7 , analgesic 8 , antioxidant, hypolipidemic 9 , anti-inflammatory 10,11 , immunomodulatory 12 and antimicrobial activity 13,14 . Many important phytoconstituents responsible for the various activities were isolated.…”

Section: Tamarindus Indica Family: Fabaceae Subfamilymentioning

confidence: 99%

Potential of Various Extracts of Tamarindus indica (Caesalpiniaceae) Leaves in the Treatment of Cancer

Dhasade¹,

Nirmal²,

Pal³

et al. 2015

Insight Cancer Research

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Background and Objective:Globally second most frequently observed disease after heart disease is "Cancer". Despite advances in cancer treatment over the past decades, the prognosis of patients with blood cancer has improved only to small extent. Thus, there is an urgent need to develop new and effective strategies for the prevention and treatment of this form of cancer. Hence, present study was undertaken to evaluate anticancer potential of leaves of Tamarindus indica Linn. (Caesalpiniaceae). Materials and Methods: The plant leaves were collected and extracted with various solvents like petroleum ether, ethanol, ethyl acetate, chloroform and water. Various extracts of leaves were screened for anticancer activity using the methods like potato disc method, onion root-tip assay and trypan blue assay by using HL-60 Cell line in dose dependent manner. Results: Petroleum ether extract of leaves of T. indica shows more potency as compared with other extracts in the treatment of cancer in all the tests performed. Conclusion: It can be concluded that petroleum ether extract of T. indica leaves have potency to prevent or manage cancer cell growth.

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Hypolipemic and antioxidant activities from Tamarindus indica L. pulp fruit extract in hypercholesterolemic hamsters

Cited by 167 publications

References 49 publications

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Development and validation of HPTLC method for estimation of gymnemic acid in microencapsulated antidiabetic polyherbal formulations

Potential of Various Extracts of Tamarindus indica (Caesalpiniaceae) Leaves in the Treatment of Cancer

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