Hypofractionated whole breast irradiation with simultaneous integrated boost in breast cancer using helical tomotherapy with or without regional nodal irradiation: A report of acute toxicities
Abstract:PurposeWe prospectively investigated the acute toxicities focusing on skin and hematologic function in breast cancer patients who received hypofractionated whole breast irradiation with simultaneous integrated boost (HF-WBI-SIB) with helical tomotherapy (HT), with or without regional nodal irradiation (RNI).MethodsThe dose of WBI and RNI was 42.4 Gy in 16 fractions. Tumor bed was prescribed to 49.6 Gy in 16 fractions simultaneously. The association between the worst grade of acute toxicities during treatment a… Show more
“…A total dose of 42.4 Gy in 16 fractions was prescribed for the PTV. The institutional dose constraint protocol for OAR was adopted from the NRG RTOG 1005 [13] , [14] .…”
“…A total dose of 42.4 Gy in 16 fractions was prescribed for the PTV. The institutional dose constraint protocol for OAR was adopted from the NRG RTOG 1005 [13] , [14] .…”
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