Arch Gen Psychiatry
 1970
DOI: 10.1001/archpsyc.1970.01750030034006
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Hypnotic Drugs and Their Effectiveness

Anthony Kales1
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Cited by 96 publications

(6 citation statements)
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“…Monroe is clear in stating that his subjects were differentiated into good sleep and poor sleep groups on the basis of responses to a sleep habits questionnaire and were not selected on the basis of being insomniacs. Moreover, the sleep characteristics of his "poor sleepers" are vastly different than those of our insomniacs and those of other studies (Kales, 1969;Karacan et al, 1971;Kales et al, 1970). Monroe's subjects have a sleep latency of only 15.6 minutes, slightly increased delta sleep (28.2%), and decreased REM sleep (16.5%).…”
Section: Discussioncontrasting
confidence: 80%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Monroe is clear in stating that his subjects were differentiated into good sleep and poor sleep groups on the basis of responses to a sleep habits questionnaire and were not selected on the basis of being insomniacs. Moreover, the sleep characteristics of his "poor sleepers" are vastly different than those of our insomniacs and those of other studies (Kales, 1969;Karacan et al, 1971;Kales et al, 1970). Monroe's subjects have a sleep latency of only 15.6 minutes, slightly increased delta sleep (28.2%), and decreased REM sleep (16.5%).…”
Section: Discussioncontrasting
confidence: 80%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Night sedation appears to be of limited value for managing sleep problems in young people, and hypnotic drugs may actually be inappropriate since their use is associated with R.E.M. sleep depression, which has been found to be already impoverished in people with mental handicap (Kales et al., 1970(Kales et al., , 1975(Kales et al., , 1983Clausen et al, 1977;Gruber, 1983;Douglas & Richman, 1984;Richman, 1985a;Bax, 1980). Recently behavioural approaches have been developed which seem to offer promise in the management of many children's problems (Anderson, 1979;Milan et al, 1984;Hewitt, 1981Hewitt, , 1985Sanders et aly 1984;Howlin, 1984;Douglas & Richman, 1984;Richman, 1985b;Richman et al, 1985).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…In terms of management, drugs would seem of very limited value (Kales, Allen, Scharf & Kales, 1970;Richman, 1983). Behavioural techniques have proved very effective in the management of many children's problems (see Yule & Carr, 1980), but there are few studies of their application to sleep problems.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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