Hypertensive Retinopathy - Prevalence, Risk Factors and Comorbids

Rao, Velure Raja Rao Mohan; Natarajaboopathy, Ravishankar; Kumar, Krishna Moorthy Sangeeth; Grace, Velure Mohan Rao Jyostnaa

doi:10.14260/jemds/2016/1553

Cited by 2 publications

(4 citation statements)

References 8 publications

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“…Установлена прямая независимая связь АГ и ГР, что соответствует данным ряда исследований [2,6], например, Beaver Dam Eye Sudy и Blue Mountains Eyes Study, где продемонстрирована связь между наличием и тяжестью АГ и микроструктурными изменениями сетчатки, включая ГР. Высокая частота ГР в изучаемой выборке >55 лет связана с широким распространением АГ и отсутствием антигипертензивной терапии у 20%.…”

Section: Discussionunclassified

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Direev

Munts

Mazurenko

et al. 2021

Cardiovasc Ther Prev

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Aim. To study associations of cardiovascular diseases and type 2 diabetes (T2D) with ophthalmic diseases in a population sample of men and women from middle to old age (Novosibirsk).Material and methods. The population cohort was initially studied in 2003-2005 (n=9360, 45-69 years old, Novosibirsk, the Health, Alcohol and Psychosocial factors in Eastern Europe (HAPIEE) project). At the second survey (2015-2017) in a random subsample (n=1011), the following ophthalmic diseases were identified: hypertensive retinopathy (HR), diabetic retinopathy (DR), cataract, glaucoma, age-related macular degeneration (AMD), optic disc abnormalities, etc.Results. The prevalence of HR signs in persons with and without hypertension (HTN) was 81 and 46%, respectively (p<0,001). This association persisted regardless of other factors (odds ratio, 2,27 (95% confidence interval: 1,78-4,17). The prevalence of AMD, cataract and DR increased in HTN, but associations were largely explained by metabolic factors in multivariate models. People with T2D more often than without T2D had signs of DR (9,3 vs 0,4%, p<0,001), AMD (22 vs 17%, p=0,042) and glaucoma (14 vs 7%, p=0,001). Associations of T2D with DR and glaucoma persisted regardless of other factors. Individuals with carotid atherosclerosis (CA) were 1,6 times more likely to have HR than those without CA when adjusted for sex, age, and smoking (p=0,013).Conclusion. In the surveyed population sample of mainly elderly people, a number of associations between cardiometabolic and common ophthalmic diseases were revealed. The identified comorbidities may have important therapeutic and prophylactic applications in an aging population.

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Section: Discussionunclassified

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Direev

Munts

Mazurenko

et al. 2021

Cardiovasc Ther Prev

View full text Add to dashboard Cite

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“…ст., что увеличивает риск развития церебральных, ретинальных, сердечных и почечных заболеваний и, следовательно, увеличивает риск осложнений, таких как ишемическая болезнь сердца, инсульт, хроническое заболевание почек и ретинопатия. По разным исследованиям [3], гипертоническую ретинопатию (ГР) можно рассматривать как один из независимых показателей системной заболеваемости и смертности.…”

Section: актуальность и распространенностьunclassified

“…Rao и соавт. [3] изучали распространенность гипертонической ретинопатии (ГР), факторов риска, сопутствующих заболеваний, с учетом влияния пола, систолического АД, длительности гипертонической ретинопатии, индекса массы тела, содержания липидов в сыворотке крови. В данном исследовании распространенность гипертонической ретинопатии среди больных с АД составила 41,5 %.…”

Section: актуальность и распространенностьunclassified

“…Выявлены корреляцион-ные взаимосвязи между гипертонической ретинопатией и высоким содержанием общего холестерина, холестерина низкой плотности и триглицеридов. Отмечено, что наличие гипертонической ретинопатии часто сопровождается ишемической болезнью сердца и инсультом [3]. новейшие сПособы для анализа артериовенозного соотношения, анализа области головки диска зрительного нерва При гиПертонической ангиоретиноПатии S. Akbar и соавт.…”

Section: актуальность и распространенностьunclassified

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Modern Aspects of Hypertensive Angioretinopathy

Lk¹,

Воробьева²,

Dgebuadze³

2019

Oftalʹmologiâ

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This literature review is devoted to modern problems of hypertensive retinopathy with arterial hypertension, as well as hypertensive retinopathy in combination diseases. The latest world studies were analyzed. Particular attention is paid to the clinical disease characteristics at the present stage with the analysis of the arterio-venous ratio, optic nerve edema (with high blood pressure figures) using an automated system, vector analysis, suggesting a new arteriovenous classification, called Web Integration (Wivern). The modern pathogenesis of hypertensive retinopathy, namely the ratio of proangiogenic and anti-angiogenic factors, the role of inflammation (C-reactive protein), the role of endothelin-1, endostatin, interleukin-8 (IL-8), and the main fibroblast growth factor (bFGF ), angiogenin and uric acid. The special importance of fundus registration is reflected with the help of the newest equipment at high figures of arterial pressure in patients with hypertensive retinopathy. It is known that according to the World Health Organization (WHO), mortality rate from cardiovascular diseases is 31 %. Hypertension is the main risk factor for coronary heart disease, myocardial infarction, heart failure, stroke, kidney disease and early death. Questions of eye blood flow in hypertensive angioretinopathy in patients with arterial hypertension (AH) are covered. Hypertensive retinopathy (HR) is a retinal disease that is caused by a prolonged increase blood pressure (BP) and leads to a decrease in vision. The data of pathophysiology are analyzed (arterial hypertension (AH) leads to thickening of the vessels of the inner membrane (intima), to thickening of the medial membrane (media) — hyperplasia of the muscular tissue followed by hyaline degeneration with the development of sclerotic changes). The questions of modern diagnostics with retinal morphological status evaluation (OCT), detection of eye fundus condition with newest fundus camers, pathogenetic aspects are discussed. This review will help to prevent the development of more severe forms of hypertensive retinopathy. This information will allow us to identify the most significant indicators in the early diagnosis of hypertension angioretinopathy.

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Hypertensive Retinopathy - Prevalence, Risk Factors and Comorbids

Cited by 2 publications

References 8 publications

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Modern Aspects of Hypertensive Angioretinopathy

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