Hypertension in cyclosporine-treated renal transplant recipients is sodium dependent1

Cardiovascular risk profile after simultaneous pancreas and kidney transplantation

“…These parameters have thus far found no attention in the field of PKT research. Hypertension is more prevalent in renal transplant recipients than in the normal population (Curtis, 1988;Kasiske, l988b), giving rise to a reduced graft survival and an increased cardiovascular mortality (Sánchez et al, 1992). The etiology of hypertension is certainly multifactorial.…”

“…The etiology of hypertension is certainly multifactorial. Contributing factors may be cyclosporine or prednisolone treatment (Sánchez et al, 1992; Fryer et al, l994),.transplant or native renal artery stenosis, renin secretion from the native 462 kidneys, rejection, or preexisting hypertension in the recipient and/or donor (Curtis et al, 1988). Although successful PKT was associated with an improvement of arterial hypertension in another study (Raja et al, 1993), in our study there was still a marked elevation of blood pressure in the successfully transplanted group (necessity of antihypertensive treatment in 65°/ of the patients).…”

Cardiovascular risk profile after simultaneous pancreas and kidney transplantation

“…These parameters have thus far found no attention in the field of PKT research. Hypertension is more prevalent in renal transplant recipients than in the normal population (Curtis, 1988;Kasiske, l988b), giving rise to a reduced graft survival and an increased cardiovascular mortality (Sánchez et al, 1992). The etiology of hypertension is certainly multifactorial.…”

“…The etiology of hypertension is certainly multifactorial. Contributing factors may be cyclosporine or prednisolone treatment (Sánchez et al, 1992; Fryer et al, l994),.transplant or native renal artery stenosis, renin secretion from the native 462 kidneys, rejection, or preexisting hypertension in the recipient and/or donor (Curtis et al, 1988). Although successful PKT was associated with an improvement of arterial hypertension in another study (Raja et al, 1993), in our study there was still a marked elevation of blood pressure in the successfully transplanted group (necessity of antihypertensive treatment in 65°/ of the patients).…”

Cardiovascular risk profile after simultaneous pancreas and kidney transplantation

“…These parameters have thus far found no attention in the field of PKT research. Hypertension is more prevalent in renal transplant recipients than in the normal population (Curtis, 1988;Kasiske, l988b), giving rise to a reduced graft survival and an increased cardiovascular mortality (Sánchez et al, 1992). The etiology of hypertension is certainly multifactorial.…”

“…The etiology of hypertension is certainly multifactorial. Contributing factors may be cyclosporine or prednisolone treatment (Sánchez et al, 1992; Fryer et al, l994),.transplant or native renal artery stenosis, renin secretion from the native 462 kidneys, rejection, or preexisting hypertension in the recipient and/or donor (Curtis et al, 1988). Although successful PKT was associated with an improvement of arterial hypertension in another study (Raja et al, 1993), in our study there was still a marked elevation of blood pressure in the successfully transplanted group (necessity of antihypertensive treatment in 65°/ of the patients).…”

Cardiovascular risk profile after simultaneous pancreas and kidney transplantation

“…These parameters have thus far found no attention in the field of PKT research. Hypertension is more prevalent in renal transplant recipients than in the normal population (Curtis, 1988;Kasiske, l988b), giving rise to a reduced graft survival and an increased cardiovascular mortality (Sánchez et al, 1992). The etiology of hypertension is certainly multifactorial.…”

“…The etiology of hypertension is certainly multifactorial. Contributing factors may be cyclosporine or prednisolone treatment (Sánchez et al, 1992; Fryer et al, l994),.transplant or native renal artery stenosis, renin secretion from the native 462 kidneys, rejection, or preexisting hypertension in the recipient and/or donor (Curtis et al, 1988). Although successful PKT was associated with an improvement of arterial hypertension in another study (Raja et al, 1993), in our study there was still a marked elevation of blood pressure in the successfully transplanted group (necessity of antihypertensive treatment in 65°/ of the patients).…”