Hypersensitivity and vaccines: an update

Barbaud, A.; Deschildre, A.; Waton, J.; Raison‐Peyron, Nadia; Tréchot, P.

doi:10.1684/ejd.2012.1842

Cited by 37 publications

(28 citation statements)

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“…Vaccine reactions are more common when administered in the arm compared to the leg and tend to occur in children after the 4th or 5th dose [3] . The most common symptoms following intramuscular vaccinations into the deltoid are erythema at the injection site and swelling in the extremity [2] . Ultrasound studies have demonstrated 111%-281% swelling of the subcutaneous soft tissues in the injected arm when compared to the contralateral arm.…”

Section: Discussionmentioning

confidence: 99%

“…The TDaP vaccination is administered as an intramuscular injection and contains additives including aluminum phosphate, formaldehyde, glutaraldehyde, and 2-phenoxyethanol. Common side effects following vaccination include but are not limited to vomiting, redness or swelling, fever, fatigue, and poor appetite [2][3][4] . Less common and more severe side effects include seizures, serious allergic reactions, and shock [5][6] .…”

Section: Introductionmentioning

confidence: 99%

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Vaccination induced rotator cuff tear: A case report

Egol

Broder

Strauss

2015

CRIM

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Intramuscular vaccinations are a necessary tool in the prevention of communicable disease in the public health realm. While commonplace, these vaccinations have the potential for adverse side effects and complications. While local skin reactions are the major cause of morbidity associated with immunizations, other more significant problems can arise. These problems can be secondary to the vaccine itself and/or the technique of administration. We present a rare and previously undescribed case of a vaccination induced rotator cuff tear occurring as the direct result of an inadvertent administration of a TDaP vaccine into the insertion of the infraspinatus and teres minor tendons on the posterior aspect of the greater tuberosity.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Vaccination induced rotator cuff tear: A case report

Egol

Broder

Strauss

2015

CRIM

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“…As with any agents, allergic (and, more often, pseudoallergic) reactions to vaccines are certainly possible (Barbaud et al, 2013). Indeed, they probably constitute the best documented category of potentially severe, and even life-threatening adverse effects of vaccination.…”

Section: Vaccine Safety: Global Evidence Basementioning

confidence: 99%

Childhood vaccination in the twenty-first century: Parental concerns and challenges for physicians

Janković¹

2019

Arhiv za farmaciju

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Vaccination is one of the most important methods of prevention of infectious disease, saving millions of lives worldwide and protecting people from potentially debilitating complications. It is therefore hailed as one of the greatest advances of science-based medicine of all times. Although repeatedly proven safe and effective, vaccination has been questioned and resented throughout its long history. Vaccine hesitancy and refusal are once again on the rise in this century, due to a complex interplay of numerous factors and circumstances. A decline in childhood vaccination rates has already resulted in resurgence of hitherto eliminated vaccinepreventable diseases in many countries, and is now perceived as a major public health threat. This decline is closely related to increasing spread of misinformation regarding vaccine safety and effectiveness, coupled with a growing anti-vaccine activism. This, among other issues, underscores the need to improve communication between healthcare workers and parents, as well as devise a more comprehensive approach to boosting vaccine confidence, where scientists, physicians, media and the general public all have important roles to play. In this paper, we discuss the phenomenology and causal structure of vaccine hesitancy and refusal, and briefly review some widespread vaccine-related questions of everyday practical importance.

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“…12 However, a review report suggested that IV might be associated with urticaria. 13 There were three case reports including 44 cases investigated the influence of IVon vasculitis and skin reactions. [14][15][16] Two observational studies including 937 patients and a safety surveillance including 4.1 million adults and children in France also reported similar side effects.…”

Section: Introductionmentioning

confidence: 99%

<p>Risk Of Urticaria In Geriatric Stroke Patients Who Received Influenza Vaccination: A Retrospective Cohort Study</p>

Lam

Shih

Chen

et al. 2019

CIA

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Urticaria is a mast cell-related disease caused severe itching and the lifetime prevalence of urticaria is about 20% in general population. Our purpose is to evaluate risk of urticaria in geriatric stroke patients received influenza vaccination (IV). Methods: In a cohort of 192,728 patients with newly diagnosed stroke aged over 65 years obtained from 23 million people in Taiwan's National Health Insurance between 2000 and 2008, we identified 9890 stroke patients who received IV and 9890 propensity score-matched stroke patients who did not receive IV. Controlling for immortal time bias, both the IV and non-IV groups were followed for one year. Urticaria events were identified during the follow-up period. We calculated the adjusted rate ratios (RRs) and 95% confidence intervals (CIs) of the one-year risk of urticaria associated with IV. Results: During the follow-up period of one year, stroke patients with IV had a significantly higher risk of urticaria compared with non-IV stroke patients (RR 1.81, 95% CI 1.47-2.23). An increased risk of urticaria in stroke patients with IV was noted in both sexes, patients 65-84 years of age, patients with comorbid medical conditions, and various time intervals of follow-up. Vaccinated stroke patients with hemorrhage (RR 4.00, 95% CI 1.76-9.10) and those who received intensive care (RR 5.14, 95% CI 2.32-11.4) had a very high risk of urticaria compared with those without IV. Conclusion: Receiving IV may be associated with an increased risk of urticaria in stroke patients. We could not infer the causality from the current results because of this study's limitations. Future investigations are needed to evaluate the possible mechanism underlying the association between IV and urticaria.

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Hypersensitivity and vaccines: an update

Cited by 37 publications

References 0 publications

Vaccination induced rotator cuff tear: A case report

Vaccination induced rotator cuff tear: A case report

Childhood vaccination in the twenty-first century: Parental concerns and challenges for physicians

<p>Risk Of Urticaria In Geriatric Stroke Patients Who Received Influenza Vaccination: A Retrospective Cohort Study</p>

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