Hyperpolarized MRS surface coil: Design and signal‐to‐noise ratio estimation

Abstract

The results demonstrated the design trade-offs to successfully design a dedicated coil for cardiac imaging in the pig with hyperpolarized 13C by developing a SNR model which allows the prediction of the coil performance. This approach can be employed for deriving SNR formulations for coil with more complex geometries.

Self-Managed Belief as Part of the “Scientific Method”: Part II—Examples From Published Scientific Work

“…This is typically tested via appropriate phantoms, usually provided by the manufacturer and/or vendor of the scanner, or specifically manufactured in the laboratory [3]. Such tests include not only signal-to-noise ratio (SNR) measurements, but also, particularly in larger, inhomogeneous RF coils, the SNR homogeneity across the sample volume [4][5][6][7][8][9][10][11][12]. Even more challenging would be the QC of hybrid systems like, e.g., PET/MRI [13].…”

Hyperpolarized 13C MRS Cardiac Metabolism Studies in Pigs: Comparison Between Surface and Volume Radiofrequency Coils

“…This coil has been previously employed for the acquisition of a CSI of a hyperpolarized [1-13 C]pyruvate phantom [10].…”

“…The surface coil inductance was calculated to be 0.673 lH [10], while the birdcage ''global'' inductance, estimated from Eq. (8) for the given geometry, was 0.423 lH.…”

“…Cardiac pyruvate metabolism measurements in pigs was described in Golman et al [8] by using a custom quadrature transmit/receive volume coil with unspecified geometry, while recently Lau et al [9] performed rapid multislice imaging for pig cardiac metabolism studies using a custom-built transmit/receive 13 C surface coil. Giovannetti et al [10] described the design trade-offs to successfully design a dedicated circular coil for cardiac imaging in the pig with hyperpolarized 13 C by developing an SNR model and successively acquiring a chemical shift image (CSI) of a hyperpolarized [1-13 C]pyruvate phantom.…”

Practical aspects of 13C surface receive coils with active decoupling and tuning circuit

“…For a circular loop coil, the coil radius must approximately equal the penetration depth to obtain optimal SNR [3]. A larger radius results in excessive noise from outside the desired volume, and a smaller radius means lack of signal from the desired volume, both degrading the SNR.…”