Hyperkeratosis Penetrans (Kyrle's Disease)

Abele, Donald C.; Dobson, Richard L.

doi:10.1001/archderm.1961.01580080107012

Cited by 13 publications

(4 citation statements)

References 6 publications

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“…Bien que les canaux perforants puissent être trouvé ensemble avec ses éléments cutanés, dans la plu part des cas ils se trouvent sans connexion avec eux, contrairem ent à ce qui se passe dans la m aladie de Kyrie. Dans la m aladie de Kyrie [31] Ilyperkeratosis follicularis et parafollicularis in cutern pénétrons -il y a aussi perforation de l'épiderme, mais du dehors au dedans, avec localisation à l'orifice des follicules pilaires et des glandes sudoripares, la masse perforante étan t constituée par de la kératine. Dans I'élas-tosis perforans la perforation se fait du dedans au dehors et la plu part des auteurs ont conclu que la masse perforante est de nature élastique.…”

Section: Discussionunclassified

Elastosis perforans

Gonçalves¹,

Assunção²,

Furtado³

et al. 1964

Dermatology

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Section: Discussionunclassified

Elastosis perforans

Gonçalves¹,

Assunção²,

Furtado³

et al. 1964

Dermatology

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“…These gradually enlarge to form reddish brown papules and papulonodules with central keratotic, cone-shaped plugs, which can be removed with a curette. The papules may be follicular (58) or extrafollicular (20). They may coalesce to form plaques (4).…”

Section: Kyrle's Disease (Kd)mentioning

confidence: 99%

Perforating Dermatoses: A Review and Report of Four Cases

Sehgal¹,

Jain²,

Thappa³

et al. 1993

The Journal of Dermatology

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Perforating dermatoses, an often overlooked entity comprised of Kyrle's disease, perforating folliculitis, reactive perforating collagenosis, elastosis perforans serpiginosa, and acquired perforating dermatosis, are succinctly described, focusing attention on their clinical features, histopathology, treatment, and pathogenesis. The literature on these facets has been extensively reviewed. In addition, three fresh cases of Kyrle's and one of perforating folliculitis have been incorporated to illustrate these conditions.

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“…Early lesions consisted of minute, slightly elevated follicular papules resembling those seen in keratosis pilaris. Older lesions were bean-sized, elevated bright brown papules with central scale [ 2 ]. Since the initial report, hundreds of cases of Kyrle disease (KD), as it is now known, have been described worldwide, 10% of which involved chronic renal failure and hemodialysis ( emedicine.medscape.com/article/1074469 ).…”

Section: Introductionmentioning

confidence: 99%

A Case of Infantile Kyrle-Flegel Disease in a 6-Year-Old Yemeni Girl

Alshami

Mohana

2016

Case Rep Dermatol

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Kyrle disease (KD) and Flegel disease (FD) are rare variants of primary perforating dermatoses, characterized by transepidermal elimination of abnormal endogenous materials. We describe a 6-year-old Yemeni girl with a 2-year history of generalized asymptomatic, small, reddish-brown keratotic papules with a lenticular central keratotic plug. Although these features are synonymous with FD, the histology of a punch biopsy was consistent with KD. The patient was otherwise healthy, and no family members had a history of similar diseases. The patient was diagnosed with KD-FD, owing to the manifestation of features associated with both diseases.

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Hyperkeratosis Penetrans (Kyrle's Disease)

Cited by 13 publications

References 6 publications

Elastosis perforans

Elastosis perforans

Perforating Dermatoses: A Review and Report of Four Cases

A Case of Infantile Kyrle-Flegel Disease in a 6-Year-Old Yemeni Girl

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