Hyperhomocysteinemia in a young woman presenting with acute myocardial infarction: Case report

Abstract

Homocysteine (Hcy), a sulfur-containing amino acid that is formed by demethylation of dietary methionine to cystein. Elevated homocysteine level is known to be associated with coronary artery disease. We present a case of acute myocardial infarction in a 25-year-old woman, associated with hyperhomocysteinaemia. Her other risk factors for coronary artery disease were smoking, a moderately high LDL level, and a family history of sudden cardiac death. This case illustrates the need to include plasma homocysteine measurement in the setting of acute coronary syndromes in women with premature atherosclerosis, even in the presence of traditional risk factors for coronary artery disease.

Acute Myocardial Infarction in a Young Man with Hyperhomocysteinemia and Pulmonary Tuberculosis

“…Several cases of STEMI with HHcy have been reported since 1997 (23)(24)(25)(26)(27). The patients (4 males and 2 females) ranged in age from 25 to 36 with homocysteine levels of 31.47-187 μmol/L.…”

Hyperhomocysteinemia as the only risk factor in a young man presenting with ST-elevation myocardial infarction

“…Multiple epidemiological studies have demonstrated a strong association between cardiovascular disease (CVD) and hyperhomocysteinemia [1]. However, there are limited reports of very young individuals with high homocysteine (Hcy) levels and no other risk factors, suffering an acute coronary syndrome (ACS) [2][3][4]. We herein report the case of a 23-year-old man with STelevation myocardial infarction (STEMI) having only very high Hcy levels as a risk factor.…”