Hyperbaric Oxygen Therapy in Deep Sternal Wound Infection After Heart Transplantation

Sternal wound dehiscence and infection are major problems for patients and health care providers. A range of risk factors, including diabetes, obesity and internal thoracic artery harvest, has been implicated. Several pathophysiological mechanisms, which may account for the development of infection, have been proposed. There is a growing body of evidence which suggests that sternal ischaemia may play a significant role in the initiation of wound infection, and that this may be exacerbated by harvest of the internal thoracic artery. Current treatments for infection include wound debridement, irrigation and tissue flap reconstruction. In addition, several novel therapies such as negative pressure dressings have been shown to be safe and useful. Hyperbaric oxygen therapy - the administration of 100% oxygen at pressures greater than atmospheric pressure - is widely used in the treatment of various chronic wounds. The mechanism whereby hyperbaric oxygen exerts its effects is being elucidated and there is a growing body of clinical evidence that supports its use. It has been suggested that there may be a role for hyperbaric oxygen therapy in the treatment of sternal infection. The theoretical mechanisms would seem plausible, but at present there is only limited evidence to support its use. This review addresses the theory and evidence supporting the role of hyperbaric oxygen therapy in the treatment of sternal wound infection.

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“…With the institution of HBO, rapid healing was observed and the wound epithilialised completely. In total, 40 HBO treatments were required [61].…”

Section: Beneficial Effects Of Hbo In Sternal Infectionmentioning

confidence: 99%

The role of hyperbaric oxygen therapy in the treatment of sternal wound infection

Mills

Bryson²

2006

European Journal of Cardio-Thoracic Surgery

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“…the risk and potential seriousness of such an infection. 3,14 In our patients, HBO was used as adjunctive therapy in addition to the main treatment modalities of wound debridement and antibiotics.…”

Section: Discussionmentioning

confidence: 99%

Preliminary Report of the Safety and Efficacy of Hyperbaric Oxygen Therapy for Specific Complications of Lung Transplantation

Higuchi

Oto

Millar

et al. 2006

The Journal of Heart and Lung Transplantation

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“…With high doses of oxygen, numerous biochemical, cellular, and physiologic effects can be achieved (Petzold, Feindt, Carl, & Gams, 1999). Clinically, HBOT is used as the primary therapy for decompression sickness, arterial gas embolism, carbon monoxide poisoning, and as an adjunctive therapy for gas gangrene, skin and flap transplants, and chronic, non-healing wounds (Leach, Rees, & Wilmshurst, 1998;Phillips, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…Ultimately, the problem wound becomes a chronic medical condition (Butcher, 1999). With HBOT, rapid healing was observed, the wound was closed and was completely epithelialized (Petzold et al, 1999). Taking into account the differences of individual patient characteristics and physiological wound indices, there are many occult variables of importance in the process of wound healing, resulting in changes in lifestyle, combined with social and environmental problems.…”

Section: Introductionmentioning

confidence: 99%

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The Efficacy of Hyperbaric Oxygen Therapy in Improving the Quality of Life in Patients With Problem Wounds

Lin

Yau²,

Lin³

et al. 2006

Journal of Nursing Research

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The unpredictable course followed by severe, chronic, non-healing wounds not only restricts the daily activities of affected patients, but also impairs their quality of life (QOL). Hyperbaric oxygen therapy (HBOT) treatment for such wounds elevates tissue oxygen content, increases cellular repair functions and the probability of wound healing, and improves the patient's QOL. This was a longitudinal, prospective study, and used a purposive sampling method. A total of 15 patients receiving HBOT at a medical center were enrolled. Data were collected by questionnaire before and after HBOT. The questionnaire included basic patient characteristics, self-perceived wound severity, wound physiological indices, and a QOL scale. The overall QOL score of the subjects after HBOT was higher than before HBOT. After HBOT, there was a positive correlation between the QOL of patients with problem wounds and the scoring of the Strauss wound classification system. After HBOT, there was a negative correlation between the QOL of patients with problem wounds and their self-perceived severity of the wound. The results were then used to provide suggestions for nursing care and additional research directions in order to effectively assist patients with problem wounds receiving HBOT, with the goal of achieving an optimal QOL.

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Hyperbaric Oxygen Therapy in Deep Sternal Wound Infection After Heart Transplantation

Cited by 25 publications

References 6 publications

The role of hyperbaric oxygen therapy in the treatment of sternal wound infection

The role of hyperbaric oxygen therapy in the treatment of sternal wound infection

Preliminary Report of the Safety and Efficacy of Hyperbaric Oxygen Therapy for Specific Complications of Lung Transplantation

The Efficacy of Hyperbaric Oxygen Therapy in Improving the Quality of Life in Patients With Problem Wounds

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