Hyperbaric oxygen therapy for multiple sclerosis

Hyperbaric oxygen therapy for the treatment of children and youth with Autism Spectrum Disorders: An evidence-based systematic review

“…Similar postulations have been made regarding chronic disabling conditions such as cerebral palsy (Mitchell & Bennett, 2014) and multiple sclerosis (Bennett & Heard, 2004). Well executed, randomized controlled trials have shown no benefit of HBOT in cerebral palsy (Mitchell & Bennett) and multiple sclerosis (Bennett & Heard).…”

Hyperbaric oxygen therapy for the treatment of children and youth with Autism Spectrum Disorders: An evidence-based systematic review

“…Similar postulations have been made regarding chronic disabling conditions such as cerebral palsy (Mitchell & Bennett, 2014) and multiple sclerosis (Bennett & Heard, 2004). Well executed, randomized controlled trials have shown no benefit of HBOT in cerebral palsy (Mitchell & Bennett) and multiple sclerosis (Bennett & Heard).…”

Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce

“…Kindwall et al didn’t show any benefit from HBOT in MS patients compared to the control group, except for a temporary improvement in bladder control which was reported by some patients [ 38 ]. Furthermore, two other main studies did not demonstrate a beneficiary from HBOT in MS patients [ 9 , 38 ].…”

Oxygen treatment reduces neurological deficits and demyelination in two animal models of multiple sclerosis

“…The current findings raise the long and vexed history of oxygen as a therapy in MS. Although many patients report that oxygen therapy reliably provides a temporary (days) reduction in symptoms such as fatigue and bladder dysfunction, such therapy is discounted by many neurologists, who are supported by Cochrane and other assessment of clinical trials [ 66 , 67 , 68 ]. The sceptical opinion has been bolstered by a belief that any beneficial effects of oxygen therapy are ‘difficult to ascribe with biological plausibility’, but we believe that such plausibility is now provided by both the findings of tissue hypoxia in neuroinflammatory disease [ 4 , 5 , 28 , 29 , 30 , 53 , 69 ], and the clearly beneficial effects of oxygen therapy in experimental models (current study and other studies [ 4 , 5 , 53 ]).…”

Hyperbaric oxygen therapy for the treatment of children and youth with Autism Spectrum Disorders: An evidence-based systematic review

“…Similar postulations have been made regarding chronic disabling conditions such as cerebral palsy (Mitchell & Bennett, 2014) and multiple sclerosis (Bennett & Heard, 2004). Well executed, randomized controlled trials have shown no benefit of HBOT in cerebral palsy (Mitchell & Bennett) and multiple sclerosis (Bennett & Heard).…”

Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce

“…Kindwall et al didn’t show any benefit from HBOT in MS patients compared to the control group, except for a temporary improvement in bladder control which was reported by some patients [ 38 ]. Furthermore, two other main studies did not demonstrate a beneficiary from HBOT in MS patients [ 9 , 38 ].…”

Oxygen treatment reduces neurological deficits and demyelination in two animal models of multiple sclerosis

“…The current findings raise the long and vexed history of oxygen as a therapy in MS. Although many patients report that oxygen therapy reliably provides a temporary (days) reduction in symptoms such as fatigue and bladder dysfunction, such therapy is discounted by many neurologists, who are supported by Cochrane and other assessment of clinical trials [ 66 , 67 , 68 ]. The sceptical opinion has been bolstered by a belief that any beneficial effects of oxygen therapy are ‘difficult to ascribe with biological plausibility’, but we believe that such plausibility is now provided by both the findings of tissue hypoxia in neuroinflammatory disease [ 4 , 5 , 28 , 29 , 30 , 53 , 69 ], and the clearly beneficial effects of oxygen therapy in experimental models (current study and other studies [ 4 , 5 , 53 ]).…”

Hyperbaric oxygen therapy for the treatment of children and youth with Autism Spectrum Disorders: An evidence-based systematic review

“…Similar postulations have been made regarding chronic disabling conditions such as cerebral palsy (Mitchell & Bennett, 2014) and multiple sclerosis (Bennett & Heard, 2004). Well executed, randomized controlled trials have shown no benefit of HBOT in cerebral palsy (Mitchell & Bennett) and multiple sclerosis (Bennett & Heard).…”

Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce

“…Kindwall et al didn’t show any benefit from HBOT in MS patients compared to the control group, except for a temporary improvement in bladder control which was reported by some patients [ 38 ]. Furthermore, two other main studies did not demonstrate a beneficiary from HBOT in MS patients [ 9 , 38 ].…”

Oxygen treatment reduces neurological deficits and demyelination in two animal models of multiple sclerosis

“…The current findings raise the long and vexed history of oxygen as a therapy in MS. Although many patients report that oxygen therapy reliably provides a temporary (days) reduction in symptoms such as fatigue and bladder dysfunction, such therapy is discounted by many neurologists, who are supported by Cochrane and other assessment of clinical trials [ 66 , 67 , 68 ]. The sceptical opinion has been bolstered by a belief that any beneficial effects of oxygen therapy are ‘difficult to ascribe with biological plausibility’, but we believe that such plausibility is now provided by both the findings of tissue hypoxia in neuroinflammatory disease [ 4 , 5 , 28 , 29 , 30 , 53 , 69 ], and the clearly beneficial effects of oxygen therapy in experimental models (current study and other studies [ 4 , 5 , 53 ]).…”