Hyperbaric Oxygen, Retinal Detachment, and Sickle Cell Anemia

Surgical Outcomes in Concurrent Sickle Cell and Diabetic Retinopathy

“…The single operation anatomic success rate in this study was 65% in eyes with retinal detachment, lower than most reported rates in eyes with retinal detachment secondary to SR or DR independently. 3,[6][7][8][9][10][11][12][13] Indeed, advanced disease and the corresponding complexity of retinal detachments that frequently characterize these cases may make primary reattachment challenging. Furthermore, active disease in the postoperative period may predispose to persistent fibrovascular proliferation and proliferative vitreoretinopathy, which may lead to recurrent retinal detachment despite initial reattachment.…”

Surgical Outcomes in Concurrent Sickle Cell and Diabetic Retinopathy

“…The single operation anatomic success rate in this study was 65% in eyes with retinal detachment, lower than most reported rates in eyes with retinal detachment secondary to SR or DR independently. 3,[6][7][8][9][10][11][12][13] Indeed, advanced disease and the corresponding complexity of retinal detachments that frequently characterize these cases may make primary reattachment challenging. Furthermore, active disease in the postoperative period may predispose to persistent fibrovascular proliferation and proliferative vitreoretinopathy, which may lead to recurrent retinal detachment despite initial reattachment.…”

Oxygen-Carrying Capacity of Perfluorohexyloctane, a Novel Eye Drop for Dry Eye Disease

“…47 In humans, hyperbaric oxygen treatment (HBOT) has been used to treat recurrent pterygium, 48 radiation-induced 49 and mitomycin C-induced 50 scleral necrosis, and to treat ischemic diseases of the anterior segment, such as anterior segment necrosis or rubeosis, iridis, or ischemic inner retinal diseases. 50 As an adjunct for scleral buckling procedures in patients with sickling hemoglobinopathies, HBOT prevented anterior segment ischemia 51 and provided significant improvement of visual acuity and visual field in patients with nonarteritic anterior ischemic optic neuropathy. 52 In addition, HBOT temporarily improved visual symptoms in patients with multiple sclerosis.…”

Surgical and Medical Perioperative Management of Sickle Cell Retinopathy: A Literature Review

“…Therefore, they recommended preoperative exchange transfusion, the avoidance of sympathomimetic agents, supplemental oxygen, avoidance of treatment or pressure on the ciliary vessels, and extraocular muscle removal. 22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”

“…22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”

Surgical Outcomes in Concurrent Sickle Cell and Diabetic Retinopathy

“…The single operation anatomic success rate in this study was 65% in eyes with retinal detachment, lower than most reported rates in eyes with retinal detachment secondary to SR or DR independently. 3,[6][7][8][9][10][11][12][13] Indeed, advanced disease and the corresponding complexity of retinal detachments that frequently characterize these cases may make primary reattachment challenging. Furthermore, active disease in the postoperative period may predispose to persistent fibrovascular proliferation and proliferative vitreoretinopathy, which may lead to recurrent retinal detachment despite initial reattachment.…”

Oxygen-Carrying Capacity of Perfluorohexyloctane, a Novel Eye Drop for Dry Eye Disease

“…47 In humans, hyperbaric oxygen treatment (HBOT) has been used to treat recurrent pterygium, 48 radiation-induced 49 and mitomycin C-induced 50 scleral necrosis, and to treat ischemic diseases of the anterior segment, such as anterior segment necrosis or rubeosis, iridis, or ischemic inner retinal diseases. 50 As an adjunct for scleral buckling procedures in patients with sickling hemoglobinopathies, HBOT prevented anterior segment ischemia 51 and provided significant improvement of visual acuity and visual field in patients with nonarteritic anterior ischemic optic neuropathy. 52 In addition, HBOT temporarily improved visual symptoms in patients with multiple sclerosis.…”

Surgical and Medical Perioperative Management of Sickle Cell Retinopathy: A Literature Review

“…Therefore, they recommended preoperative exchange transfusion, the avoidance of sympathomimetic agents, supplemental oxygen, avoidance of treatment or pressure on the ciliary vessels, and extraocular muscle removal. 22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”

“…22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”

Surgical Outcomes in Concurrent Sickle Cell and Diabetic Retinopathy

“…The single operation anatomic success rate in this study was 65% in eyes with retinal detachment, lower than most reported rates in eyes with retinal detachment secondary to SR or DR independently. 3,[6][7][8][9][10][11][12][13] Indeed, advanced disease and the corresponding complexity of retinal detachments that frequently characterize these cases may make primary reattachment challenging. Furthermore, active disease in the postoperative period may predispose to persistent fibrovascular proliferation and proliferative vitreoretinopathy, which may lead to recurrent retinal detachment despite initial reattachment.…”

Oxygen-Carrying Capacity of Perfluorohexyloctane, a Novel Eye Drop for Dry Eye Disease

“…47 In humans, hyperbaric oxygen treatment (HBOT) has been used to treat recurrent pterygium, 48 radiation-induced 49 and mitomycin C-induced 50 scleral necrosis, and to treat ischemic diseases of the anterior segment, such as anterior segment necrosis or rubeosis, iridis, or ischemic inner retinal diseases. 50 As an adjunct for scleral buckling procedures in patients with sickling hemoglobinopathies, HBOT prevented anterior segment ischemia 51 and provided significant improvement of visual acuity and visual field in patients with nonarteritic anterior ischemic optic neuropathy. 52 In addition, HBOT temporarily improved visual symptoms in patients with multiple sclerosis.…”

Surgical and Medical Perioperative Management of Sickle Cell Retinopathy: A Literature Review

“…Therefore, they recommended preoperative exchange transfusion, the avoidance of sympathomimetic agents, supplemental oxygen, avoidance of treatment or pressure on the ciliary vessels, and extraocular muscle removal. 22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”

“…22 Soon after this, Freilich and Seelenfreund (1973) reported the successful treatment of PSR in three patients via SB procedures in a hyperbaric chamber. 25 However, these methods were not replicated by other authors.…”