Hydroxyapatite Cement: II. Obliteration and Reconstruction of the Cat Frontal Sinus

Hydroxyapatite Cement in Craniofacial Skeletal Reconstruction and Its Effects on the Developing Craniofacial Skeleton

“…If direct neural tissue contact were to occur, we would anticipate no adverse wound healing effects, and the expected histological response (although unknown and not the focus of the present study) would be the same as direct surgical manipulation or incision of neural tissue. Supporting the findings of a previous study by Friedman et al, 13 we found HAC to be effective in obliteration of the frontal sinus. In conjunction with clinical evidence, computed tomography demonstrated complete obliteration of the left frontal sinus, with no evidence of cystic structures that would suggest mucocele formation.…”

“…In addition, histomorphometry revealed rapid replacement of the implant by bone. In comparison with the results of the study by Friedman et al 13 of adult cats, which showed 5% bony replacement of HAC in 6 months, our study produced 44% to 50% bony replacement of HAC in 5 months when kittens were used. This finding demonstrates that HAC implants are able, at least in part, to respond to dif- ferent physiologic wound environments with different performance in the form of more accelerated conversion to bone when placed in the developing skeleton.…”

Reconstruction of the Frontal Sinus and Frontofacial Skeleton With Hydroxyapatite Cement

“…Hydroxyapatite cement has been shown in this study to confirm the findings of previous animal experimentation, 7 ie, osseointegration and osseoconversion of the implant to bone. Figure 2 illustrates the histological features from a core biopsy specimen of a patient explant.…”

Frontal Bone Remodeling for Gender Reassignment of the Male Forehead: A Gender-Reassignment Surgery

“…Since 2002, we have used a bone source for cranial vault reconstruction and recontouring, especially for augmentation of the forehead in nonsyndromic and non-post-tumor patients without seeing any postoperative complications [21] such as inflammatory reactions with swelling or mild redness over an 8 year period, which is in agreement with others [19, 21–24, 27–35, 39, 40]. Perhaps because no previous trauma or infections took place before frontal bone remodeling gender reassignment of the bony forehead in conjunction with HAC, augmentation has been a safe procedure without any major complications over the past several years in our hands.…”