Journal of Chromatography A volume 1218, issue 52, P9336-9344 2011 DOI: 10.1016/j.chroma.2011.10.067 View full text
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Ira S. Lurie, Li Li, Steven G. Toske

Abstract: The use of hydrophilic interaction chromatography (HILIC) with sub 2 μm particle columns for the analysis of drugs and related compounds of forensic interest is described. This technique uses a high organic/low aqueous buffered mobile phase with a polar stationary phase, and is excellent for the separation of many of the charged solutes that are found in forensic drug exhibits. In this study, HILIC is investigated for 11 solutes of forensic interest, including weak bases, weak acids, and a neutral solute. In a…

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