Hydrogen‐Terminated Si Nanowires as Label‐Free Colorimetric Sensors in the Ultrasensitive and Highly Selective Detection of Fluoride Anions in Pure Water Phase

Wang, Hui; Fan, Pei-Hong; Tong, Bin; Dong, Yuping; Ou, Xuemei; Li, Fan; Zhang, Shun

doi:10.1002/adfm.201401632

Cited by 14 publications

(5 citation statements)

References 41 publications

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“…Fluoride has proven difficult to detect in water, primarily due to the extensive solvent cluster of water around fluoride (Cabarcos et al, 1999;Zhan and Dixon, 2004), with which a sensor would have to compete. In such instances, surfactants such as cetyltrimethylammonium bromide (CTAB) have sometimes been employed to dissolve the sensor in a micellular environment (Hu et al, 2010;Calderon-Ortiz et al, 2012;Elsayed et al, 2013;Roy et al, 2015;Wang et al, 2015;Qiu et al, 2016;Wallabregue et al, 2016). Phase-transfer catalysts such as tetra-n-butylammonium hydrogensulfate (TBAS) can be used in tandem to aid transport of the analyte into the micelle (Lopez-Alled et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

A Colorimetric Chemosensor Based on a Nozoe Azulene That Detects Fluoride in Aqueous/Alcoholic Media

et al. 2020

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Colorimetry is an advantageous method for detecting fluoride in drinking water in a resource-limited context, e. g., in parts of the developing world where excess fluoride intake leads to harmful health effects. Here we report a selective colorimetric chemosensor for fluoride that employs an azulene as the reporter motif and a pinacolborane as the receptor motif. The chemosensor, NAz-6-Bpin, is prepared using the Nozoe azulene synthesis, which allows for its rapid and low-cost synthesis. The chemosensor gives a visually observable response to fluoride both in pure organic solvent and also in water/alcohol binary solvent mixtures.

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Section: Introductionmentioning

confidence: 99%

A Colorimetric Chemosensor Based on a Nozoe Azulene That Detects Fluoride in Aqueous/Alcoholic Media

et al. 2020

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“…We have developed silicon nanowire field effect transistors (SiNW FETs) − as the sensing matrices for the detection and discrimination between disease breathprints. As representative diseases, we chose gastric cancer (GC), lung cancer (LC), and asthma and chronic obstructive pulmonary disease (COPD).…”

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confidence: 99%

Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath

et al. 2016

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Abstract:Two of the biggest challenges in medicine today are the need to detect diseases in a non-invasive manner, and to differentiate between patients using a single diagnostic tool. The current study targets these two challenges by developing a molecularlymodified Silicon Nanowire Field Effect Transistors (SiNW FETs) and showing its use in the detection and classification of many disease breathprints (lung cancer, gastric cancer, asthma and Chronic Obstructive Pulmonary Disease). The fabricated SiNW FETs are characterized and optimized based on a training set that correlated their sensitivity and selectivity towards volatile organic compounds (VOCs) linked with diseased states. The best sensors obtained in the training set are then examined under real-world clinical conditions, using breath samples from 374 subjects. Analysis of the clinical samples showed that the optimized SiNW FETs can detectand discriminate between almost all binary comparisons of the diseases under examination with >80% accuracy. Overall, this approach has the potential to support detection of many diseases in a direct positive way, which can reassure patients and prevent numerous negative investigations. 3Physicians are always challenged by the need to give the correct diagnosis as early in the onset of a disease is possible, whether the disease-related symptoms are absent or not evident.1 Symptoms are not always characteristic of one particular disease; overlap of symptoms is common in, for example, lung diseases. 2 Patients with different respiratory diseases, such as malignant or benign tumors, or substantially less severe diseases, may have similar symptoms, e.g. cough, chest pain, difficulty to breathe, etc. These symptoms may be characteristic of lung cancer (LC), pneumonia, asthma, and chronic obstructive pulmonary disease (COPD). 1,2Therefore, it is of particular clinical importance to find a diagnostic tool capable of distinguishing between these diseases. A diagnostic tool that involves no needle, surgery and/or active materials and/or radioactive exposure would have a benefit.A highly promising approach that could meet the aforementioned need is based on the detection and classification of the disease breathprint, viz. the chemical profiles of highly-and semi-VOCs in exhaled breath linked with disease. [3][4][5][6][7][8][9][10][11][12][13][14][15] The rationale behind this approach relies on the fact that VOCs generated by cellular metabolic pathways during a specific disease circulate in the blood stream and diffuse into exhaled breath, which is easily sampled. 4,16,17 In certain instances, analysis of breathprints offers several potential advantages, such as: (a) breath samples are non-invasive and easy to obtain; (b) breath contains less complicated mixtures than either serum or urine; and (c) breath testing has the potential for direct and real-time diagnosis and monitoring. 3,18-21Several mass-spectrometry and spectroscopy studies have shown that the breathprint of a specific disease differs from that of healthy control...

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“…So far, different methods are available for fluoride detection, such as ion-selective electrodes, 16,17 chromatography, 18,19 spectrophotometry, 20 and Willard and Winter methods. Apart from these, some fluoride probes have also been recently reported based on different sensing mechanisms, namely desilylation, [21][22][23] fluoride-hydrogen bonding, 24,25 boron-fluoride complexation, 1,26 colorimetric changes, [27][28][29] fluorescence quenching, 30 and fluorescence enhancement. 4,21,31,32 In spite of the fact that every method has its own advantages and disadvantages, fluorescence based fluoride anion sensing methods have received more attention in recent years because of their low cost, simplicity, sensitivity, and high selectivity in the presence of anionic species.…”

Section: Introductionmentioning

confidence: 99%

“…4,21,31,32 In spite of the fact that every method has its own advantages and disadvantages, fluorescence based fluoride anion sensing methods have received more attention in recent years because of their low cost, simplicity, sensitivity, and high selectivity in the presence of anionic species. Different nanomaterials, such as Au, 33 CdSe/ZnS, 34 silica, 35 C dots, 36 Si nanowires, 28 etc. have been used as fluorescence probes for fluoride ion detection.…”

Section: Introductionmentioning

confidence: 99%

Fluorometric selective detection of fluoride ions in aqueous media using Ag doped CdS/ZnS core/shell nanoparticles

Boxi

Paria

2016

Dalton Trans.

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The presence of fluoride ions in drinking water plays an important role in human health. For that reason, maintaining the optimum concentration of fluoride ions in drinking water is essential, as both low and excess (above the permissible level) concentrations can cause different health problems, such as fluorosis, urolithiasis, kidney failure, cancer, and can even lead to death. So, development of a simple and low cost method for the detection of fluoride ions in water is highly desirable. In this study, a fluorometric method based on Ag-CdS/Ag-ZnS core/shell nanoparticles is developed for fluoride ion detection. The method was tested in aqueous solution at different pH values. The selectivity and sensitivity of the fluorescence probe was checked in the presence of other anions (Cl(-), Br(-), I(-), NO3(-) SO4(2-), HCO3(-), HPO4(2-), CH3COO(-), and H2PO4(-)) and found there is no significant interference of these associated ions. The fluoride ion concentration was varied in the range 190-22 800 μg L(-1) and a lower detection limit was obtained as 99.7 μg L(-1).

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Hydrogen‐Terminated Si Nanowires as Label‐Free Colorimetric Sensors in the Ultrasensitive and Highly Selective Detection of Fluoride Anions in Pure Water Phase

Cited by 14 publications

References 41 publications

A Colorimetric Chemosensor Based on a Nozoe Azulene That Detects Fluoride in Aqueous/Alcoholic Media

A Colorimetric Chemosensor Based on a Nozoe Azulene That Detects Fluoride in Aqueous/Alcoholic Media

Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath

Fluorometric selective detection of fluoride ions in aqueous media using Ag doped CdS/ZnS core/shell nanoparticles

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