Hydrogels in Wound Management

Caló, Enrica; Ballamy, Lucy; Khutoryanskiy, Vitaliy V.

doi:10.1201/9781315152226-7

Cited by 8 publications

(12 citation statements)

References 37 publications

(55 reference statements)

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“…Due to their remarkable properties, hydrogels can be included in the category of "smart" materials. In the medical field, hydrogels are used for wound treatment, drug delivery, cell therapies, tissue engineering, the manufacture of medical devices and biosensors 45‐47 . The use of hydrogels in the therapeutic strategy of patients suffering from wounds brings many benefits such as avoiding complications, shortening the healing time of the wound, increasing the quality of life of patients and obtaining a better therapeutic result.…”

Section: Hydrogels For Wound Healing Applicationsmentioning

confidence: 99%

“…Hydrogels that respond to external stimuli allow controlled release of drugs or monitoring of the healing process. 3,45 Many research projects are now focusing on the development of new devices for wound management. There are some essential aspects that must be present in the ideal wound care system.…”

Section: Hydrog El S For Wound He Aling Appli C Ati On Smentioning

confidence: 99%

“…A great advantage is that the intrinsic properties of hydrogels can be improved by adding active compounds, such as antibiotics, nanoparticles, stem cells and growth factors (Table 1). Hydrogels that respond to external stimuli allow controlled release of drugs or monitoring of the healing process 3,45 …”

Section: Hydrogels For Wound Healing Applicationsmentioning

confidence: 99%

“…In the medical field, hydrogels are used for wound treatment, drug delivery, cell therapies, tissue engineering, the manufacture of medical devices and biosensors. [45][46][47] The use of hydrogels in the therapeutic strategy of patients suffering from wounds brings many benefits such as avoiding complications, shortening the healing time of the wound, increasing the quality of life of patients and obtaining a better therapeutic result. Hydrogels have properties that make them ideal for the treatment of deep wounds, such as non-adhesiveness, moisture retention, gas permeability, exudate absorption, biocompatibility and are comfortable for the patient.…”

Section: Hydrog El S For Wound He Aling Appli C Ati On Smentioning

confidence: 99%

See 3 more Smart Citations

Wound healing applications of creams and “smart” hydrogels

Stan

Tănase

Avram³

et al. 2021

Experimental Dermatology

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Section: Hydrogels For Wound Healing Applicationsmentioning

confidence: 99%

Section: Hydrog El S For Wound He Aling Appli C Ati On Smentioning

confidence: 99%

Section: Hydrogels For Wound Healing Applicationsmentioning

confidence: 99%

Section: Hydrog El S For Wound He Aling Appli C Ati On Smentioning

confidence: 99%

See 2 more Smart Citations

Wound healing applications of creams and “smart” hydrogels

Stan

Tănase

Avram³

et al. 2021

Experimental Dermatology

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show abstract

“…In the swollen state, the presence of cross-links between the elastomer chains provides them with favourable mechanical properties. This together with their biocompatibility make hydrogels highly sought after for several biomedical applications such as drug delivery systems and contact lenses, refer Caló and Khutoryanskiy [2015].…”

Section: Introductionmentioning

confidence: 99%

Transient stability analysis of composite hydrogel structures based on a minimization-type variational formulation

Sriram¹,

Polukhov²,

Keip³

2021

Preprint

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We employ a canonical variational framework for the predictive characterization of structural instabilities that develop during the diffusion-driven transient swelling of hydrogels under geometrical constraints. The variational formulation of finite elasticity coupled with Fickian diffusion has a two-field minimization structure, wherein the deformation map and the fluid-volume flux are obtained as minimizers of a time-discrete potential involving internal and external energetic contributions. Following spatial discretization, the minimization principle is implemented using a conforming Q 1 RT 0 finiteelement design, making use of the lowest-order Raviart-Thomas-type interpolations for the fluid-volume flux. To analyze the structural stability of a certain equilibrium state of the gel satisfying the minimization principle, we apply the local stability criterion on the incremental potential, which is based on the idea that a stable equilibrium state has the lowest potential energy among all possible states within an infinitesimal neighborhood. Using this criterion, it is understood that bifurcation-type structural instabilities are activated when the coupled global finite-element stiffness matrix loses its positive definiteness. This concept is then applied to determine the onset and nature of wrinkling instabilities occurring in a pair of representative film-substrate hydrogel systems. In particular, we analyze the dependencies of the critical buckling load and mode shape on the system geometry and material parameters.

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Exploring Nanohydrogels: Crafting Innovations for Biomedical Advancements

Sharma,

Ghosh,

Sengupta

et al. 2024

ChemistrySelect

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Here in, we discuss different types of nanohydrogels in the field of biomedicine, highlighting their unique properties such as size, biocompatibility, and tuneable drug release capabilities. Nanohydrogels are considered versatile tools for applications in tissue engineering, drug delivery, and diagnostics, with the ability to target specific sites and release therapeutic agents in a controlled manner. The controlled‐release characteristics of nanohydrogels are particularly emphasized for targeted drug delivery, potentially transforming therapies for conditions like cancer by maximizing treatment efficacy while minimizing damage to healthy tissues. Several research articles published on nanohydrogels has been steadily increasing over the years, indicating growing interest and research activity in this field. This review provides an overview of contemporary methodologies employed in nanohydrogel design, their utilization in biomedical contexts, and their pivotal role in shaping advanced therapeutics. Recent investigations on nanohydrogels are scrutinized for their extensive utility in devising strategies conducive to finely tuned biological applications. Challenges and obstacles associated with the nanohydrogel technology in biomedicine also has been discussed. Cautious handling of the interaction of nanohydrogels with complex biological systems is also emphasized for the successful integration of this technology into medical applications.

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Hydrogels in Wound Management

Cited by 8 publications

References 37 publications

Wound healing applications of creams and “smart” hydrogels

Wound healing applications of creams and “smart” hydrogels

Transient stability analysis of composite hydrogel structures based on a minimization-type variational formulation

Exploring Nanohydrogels: Crafting Innovations for Biomedical Advancements

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