Hydroa vacciniforme

Abstract

Two patients with hydroa vacciniforme, a rare photodermatosis of unknown etiology, demonstrated distinctive scarring and vesiculobullous skin lesions on light-exposed body areas. Results of blood and urine porphyrin studies were normal, and no systemic abnormalities were noted. A small bullous lesion was produced in normal skin in case 1 with 15 times the minimal erythema dose of ultraviolet energy. The conditions of both patients improved while they were taking beta carotene orally.

Actinic prurigo: a case report with successful induction of skin lesions

“…Recently, Bickers et al (1978) reported successful reproduction of the skin lesions in hydroa vacciniforme with large dose (t5 MED) of UV-B within 24 h. The intensive irradiations of UV-B followed by the careful observation ofthe test sites may be a necessary step for the differential diagnosis of actinic prurigo and hydroa vacciniforme.…”