Human Rotavirus Serotype G9, São Paulo, Brazil, 1996–2003

Carmona, Rita de Cássia Compagnoli; Timenetsky, María do Carmo Sampaio Tavares; Morillo, Simone Guadagnucci; Richtzenhain, Leonardo José

doi:10.3201/eid1206.060307

Cited by 41 publications

(44 citation statements)

References 33 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Genotype P [4] was found in 19 (35.2%) samples alone, and in 11 samples with mixed infections (Tables 3 and 4). P [8] was found in 16 (29.6%) samples alone and in 12 mixed infections. P[6-M37 like] was found in 3 samples alone and in 9 samples with mixed infections.…”

Section: Resultsmentioning

confidence: 99%

“…P[6-Gottfried like] was not found alone, but was found in 6 samples with mixed P genotypes. P [8] genotype was detected mostly associated with G1 and P [4] was detected mostly in combination with G2 rotaviruses (Table 4). From three samples characterized as P[6-M37 like], one was associated with G2 genotype and two with mixtures of G genotypes (Table 4).…”

Section: Resultsmentioning

confidence: 99%

“…In Brazil, the frequency of group A rotavirus infection was found to be between 12 and 42% (7,8,25,38) and about 80.000 children are hospitalized for the infection (25).…”

Section: Introductionmentioning

confidence: 99%

“…Surveys around the globe indicates that G1P [8], G2P [4], G3P [8] and G4P [8] are the most common G and P types combinations (24,38,40). However, recently, genotypes G5, G8, G9, G11 and G12, and/or new combinations of G and P were identified in Latin America and in other parts of the world (10,38,41).…”

Section: Introductionmentioning

confidence: 99%

“…For VP4 genotyping, second amplification was done with specific primers to VP4 genotypes P [4], P2A [6], P [8], P [9] and P [10] (14); P [1], P [5], P2B [6], P [7] and P [11] (19).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Serological and molecular diversity of human rotavirus in São Paulo, Brazil

Munford

Souza

Caruzo

et al. 2007

Braz. J. Microbiol.

View full text Add to dashboard Cite

From a total of 187 fecal samples from children with ages between 0 and 5 years, collected in the Hospital Universitário -USP, Brazil, from 1994 to 1996, 54 (28.9%) were positive for rotavirus. Positive samples were characterized by electropherotyping, subgrouping, G serotype and genotype and P genotype. Rotavirus electropherotypes were characterized in four different long genome patterns (38.9%), one short genome pattern (34.0%) and 18.0% were characterized as an unusual pattern. Subgroup I was found in 38.9% strains, subgroup II in 50.0% and 7.7% was subgroup nonI-nonII. For G serotypes, G2 was found in 59.3%, G1 was identified in 33.3% of strains, two samples showed mixtures of G1+G2 and one sample was G1+G3. Ten samples characterized as serotype G2 showed a long eletropherotype. Genotype G2 was the most frequently and was found in 37 (44.0%) samples (23 samples as a single genotype and 14 as mixtures of genotypes). G1 was found in 15 samples. G3 and G4 was detected mainly in mixtures of genotypes and G5, G6 and G9 were identified only in mixtures. A total of 20 (38.5%) samples were characterized as G genotype mixtures and P mixtures were found in 16 (29.6%) samples. P [4] was found in 55.6% of samples, P[8] in 51.9% and P[6-M37 like] in 22.3% of cases. P[6-Gottfried like] and P[11] were detected only in mixtures. One sample with G6 specificity, mixed with a G2 rotavirus and a P[11] strain, mixed with P[4] and P[8]strain was described for the first time in Latin America.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…In Brazil, the frequency of group A rotavirus infection was found to be between 12 and 42% (7,8,25,38) and about 80.000 children are hospitalized for the infection (25).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…For VP4 genotyping, second amplification was done with specific primers to VP4 genotypes P [4], P2A [6], P [8], P [9] and P [10] (14); P [1], P [5], P2B [6], P [7] and P [11] (19).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Serological and molecular diversity of human rotavirus in São Paulo, Brazil

Munford

Souza

Caruzo

et al. 2007

Braz. J. Microbiol.

View full text Add to dashboard Cite

show abstract

Brazilian P[8],G1, P[8],G5, P[8],G9, and P[4],G2 rotavirus strains: Nucleotide sequence and phylogenetic analysis

Araújo

Assis

Fialho

et al. 2007

Journal of Medical Virology

View full text Add to dashboard Cite

Rotavirus epidemiological surveys with molecular analysis of strains are required for gastroenteritis control and prevention. Twenty-nine human rotavirus strains detected in Rio de Janeiro, Brazil, from 1986 to 2004 were characterized as P[8],G1, P[8],G5, P[8],G9, and P[4],G2 genotypes. The VP7 genes were sequenced and phylogenetic analysis was performed. Strains of genotype G1 revealed two distinct lineages, G1-3 and G1-4; strains of genotype G2 grouped in lineage G2-1; G5 strains clustered with other Brazilians G5 strains and G9 strains were closely related to each other in lineage G9-3, distinct from the original G9 strains detected in 1980s. The VP4 genes were analyzed and P[8] strains fell into two major genetic lineages, P[8]-2 and P[8]-3. Our findings document an intragenotype diversity represented by lineages and sublineages within rotavirus circulating in Rio de Janeiro from 1986 to 2004, before application of a vaccine (Rotarix) in Brazil. This report emphasizes the importance of continuing monitor genotypes to verify if uncommon strains or newly strains are emerging to be specifically addressed in future vaccine trials.

show abstract

Prevalence of VP4 and VP7 genotypes of human rotavirus in Ecuadorian children with acute diarrhea

Naranjo

Cedeño

Terán³

et al. 2008

Journal of Medical Virology

View full text Add to dashboard Cite

The objective of the present study was to determine rotavirus etiology and prevalence of the different rotavirus serotypes in Ecuadorian children younger than 5 years of age with gastroenteritis. Children (729) less than 5 years of age with acute diarrhea from either public or private primary health care centers in 10 different provinces of Ecuador, between March 2006 and August 2006 were included in the study. Rotavirus infection was diagnosed using a commercial immunoenzymatic test. Rotavirus isolated from stool samples was genotyped. Rotavirus was detected in the feces of 269 of the 729 children (37%) with diarrhea. The most prevalent G genotypes were G9 (46.1%) and G2 (27.2%), while the predominant P genotypes were P[8] (57%) and P[4] (29.5%). Among the single infections, the predominant P/G combinations were: P[8]G9 (56.9%) and P[4]G2 (32.6%). The present countrywide survey is one of the major studies for one single season in Latin America and the first in its class in Ecuador. The value of expanding laboratory capability throughout Latin America in order to monitor rotavirus strains over time, with special attention directed at those strains obtained from children who experience vaccine failure, is critical. Only continuous monitoring of rotavirus disease burden and genotype surveillance will provide this information.

show abstract

Human Rotavirus Serotype G9, São Paulo, Brazil, 1996–2003

Abstract: Diverse rotavirus strains are present, and frequency of G9 is high.

Cited by 41 publications

References 33 publications

Serological and molecular diversity of human rotavirus in São Paulo, Brazil

Serological and molecular diversity of human rotavirus in São Paulo, Brazil

Brazilian P[8],G1, P[8],G5, P[8],G9, and P[4],G2 rotavirus strains: Nucleotide sequence and phylogenetic analysis

Prevalence of VP4 and VP7 genotypes of human rotavirus in Ecuadorian children with acute diarrhea

Contact Info

Product

Resources

About