Human immunodeficiency virus/acquired immunodeficiency syndrome and infertility: emerging problems in the era of highly active antiretrovirals

Kushnir, Vitaly A.; Lewis, William

doi:10.1016/j.fertnstert.2011.05.094

Cited by 86 publications

(95 citation statements)

References 117 publications

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“…The CD4 cell count levels were used as marker for severity of HIV disease. Semen parameters were compared between patients with CD4 counts level below and above 350cells/mm 3. Of the five semen parameters (table 4) compared, HIV positive participants with more severe diseases (CD4 < 350cells/mm 3 ) had significantly lower mean sperm volume (p=0.003), sperm concentration (p=0.0002) and total sperm concentration (p<0.001) compared with HIV positive participants with less severe diseases (CD4 >350cells/mm 3 ). No statistical significant difference were observed in mean % normal morphology (p=0.34) and mobility (p=0.75).…”

Section: Sperm Quality and Severity Of Hiv Diseases Among Hiv Positivmentioning

confidence: 99%

“…2 As a result of the very high morbidity and mortality associated with HIV infection then, fertility issues were relegated to the background as the major thrust was to reduce mortality and transmission of Infections. 3 In the last decade, the grin picture has changed as the development and introduction of highly active antiretroviral therapy (HAART) has transformed the prognosis for HIV-infected individuals. The resultant increased longevity and quality of life has caused an increasing number of reproductive-age heterosexual HIV positive couples desiring to have children.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Semen quality of male partners of infertile couples living with HIV infection

Ezechi

Wapmuk

Ohihoin

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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Section: Sperm Quality and Severity Of Hiv Diseases Among Hiv Positivmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Semen quality of male partners of infertile couples living with HIV infection

Ezechi

Wapmuk

Ohihoin

et al. 2016

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

“…Other factors like chronic anovulation, premature ovarian failure have been implicated but there is no clear evidence [7]. HIV infection is also known to adversely affect male reproductive system with orchitis, leukospermia and hypogonadism being more common Semen parameters like semen volume, morphology, concentration and motility are significantly impaired [7].…”

Section: Effect Of Hiv On Fertilitymentioning

confidence: 99%

“…HIV infection is also known to adversely affect male reproductive system with orchitis, leukospermia and hypogonadism being more common Semen parameters like semen volume, morphology, concentration and motility are significantly impaired [7]. Prior to investigating an HIV infected couple for infertility it is recommended that both male and female partners undergo a thorough sexual health examination and screening for concurrent STI.…”

Section: Effect Of Hiv On Fertilitymentioning

confidence: 99%

HIV and Preconception- a Review

Hegde¹,

Kamath²,

Sharma³

2013

Med-Science

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“…Many HPV infections may also develop into cervical cancers that may cause irreparable damage to reproductive organs, or compromise a woman's ability to carry a pregnancy to term (Depuydt et al, 2011). There is also some evidence that the medications and treatments required to treat viral STIs may be toxic to neonatal development (Kushnir & Lewis, 2011). Finally, it is important to note that all STIs-both bacterial and viral-come with an increased risk of contracting other STIs, compounding a woman's risk for infertility (CDCP, 2015d).…”

Section: Risk For Infertility As Function Of Sexual Identity Sexualmentioning

confidence: 99%

Risk for Infertility as a Function of Sexual identity, Sexual Behavior, and Race Among Women in the United States

Blanchfield¹

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Infertility affects approximately ten percent of women in the United States every year. There has been consistent evidence indicating that sexually transmitted infections (which are commonly cited risks for infertility) disproportionately affect non-White women, and racial minority women are nearly twice as likely as White women to experience infertility issues. However, comparable research that addresses the prevalence of sexually transmitted infections and/or infertility among sexual minority women is limited and inconsistent. Varied reports are due in part to researchers' restricted focus on behavior rather than identity-based approaches to sexual minority women's health experiences. The dearth of information is exacerbated by the operating definition of infertility (i.e., the failure to conceive following 12 months of heterosexual intercourse), which does not typically apply to sexual minority women. A framework of stratified reproduction, which takes into account the contribution of systemic inequities to minority women's reproductive health, may help reveal and explain disparities in risk for infertility among racial and sexual minority-identified women.Moreover, stratified reproduction also suggests that an underlying social experience common to both racial minority and sexual minority women (such as adolescent housing instability), may partially explain disparities in risk for infertility.The present study examined the sexually transmitted infection prevalence and overall risk for infertility among women in the United States as a function of race, sexual identity, and-so as to better differentiate the role of identity versus behavior-sexual behavior. The present study thus had three aims. The first aim was to establish the rates of various sexually transmitted infections that can threaten women's fertility as a function of sexual identity, sexual behavior, and race. The second aim was to determine how other commonly studied risk factors for infertility, (i.e., certain reproductive illnesses, alcohol consumption, tobacco use, and high or low bodyweight) might also be associated with sexual identity, sexual behavior, and race. These factors were examined in conjunction with RISK FOR INFERTILITY AS FUNCTION OF SEXUAL IDENTITY, SEXUAL BEHAVIOR, AND RACE AMONG U.S. WOMEN iv findings about sexually transmitted infections to construct a novel Risk for Infertility measure that allowed for a comparative risk assessment among women as a function of their racial identity, sexual identity, and sexual behavior. The third and final aim of this study was to test whether adolescent housing instability-for which sexual minority and racial minority individuals have both been at increased risk-might mediate the disparity in risk for infertility that emerged as a function of sexual identity, sexual behavior, and race among participants.The sample consisted of 4,990 women (representative of over 53 million women in the United States), ages 15-44, who participated in the 2011-3013 National Survey of Family Growth. As ...

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Human immunodeficiency virus/acquired immunodeficiency syndrome and infertility: emerging problems in the era of highly active antiretrovirals

Cited by 86 publications

References 117 publications

Semen quality of male partners of infertile couples living with HIV infection

Semen quality of male partners of infertile couples living with HIV infection

HIV and Preconception- a Review

Risk for Infertility as a Function of Sexual identity, Sexual Behavior, and Race Among Women in the United States

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