Human Herpesvirus 8-Specific DNA Sequences in Primary Cutaneous B-Cell Lymphomas

Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients

“…[6][7][8] Oligonucleotide primers for B burgdorferi PCR. Oligonucleotide primers for PCR amplification reactions were designed by Wienecke et al 9 on the basis of the B burgdorferi-specific gene described by Rosa et al 10 The outer primer pair (Bb1 and Bb2) is flanking a 171-base pair (bp) fragment (nucleotide position/np 143-np313), whereas the inner primer pair (Bb 3 and Bb4) spans a 92-bp amplification product (np160-np251).…”

Defectos de la apoptosis en el linfoma cutáneo

“…Sin embargo, se ha demostrado el genoma del HHV-8 en el 5 a 10 % de la población sana en ciertas zonas geográficas, lo cual sugiere la posibilidad de que la positividad del HHV-8 represente un epifenómeno. Por lo tanto, son necesarios más estudios para evaluar el papel del HHV-8 en la patogénesis de las enfermedades linfoproliferativas cutáneas 25 .…”

Radiation Therapy and Skin Cancer

“…Putative etiologic agents include Borrelia spp., Epstein-Barr virus, or human herpes viruses. (Nagore et al, 2000;Zochling et al, 1998). Interestingly, there are cases of presumed benign reactive lymphoid hyperplasia (pseudolymphoma) simulating CBCL that have occurred secondary to drugs, vaccinations, arthropod bites, or chronic folliculitis.…”