Background and Objectives: There are a number of unique processes seen in the developing fetus that cease post-partum including that tumors rarely form, and scar-less wound healing and digit regeneration occur. In addition, cancer lines have been "reprogrammed" by co-culture with embryonic extracellular matrix (ECM). Methods and Results: We have developed a naturally secreted human ECM (hECM) with embryonic-like characteristics which is secreted by neonatal fibroblasts grown in microcarrier suspension culture…
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