HPLC-ESI-QqQ based standardization, mutagenic and genotoxic potential of methanol extract of Ziziphus mauritiana Lam leaves

Ramar, Mohan Kumar; Dhayanandamoorthy, Yamini; Ramachandran, Shiyam Sundar; Kandasamy, Ruckmani

doi:10.1016/j.jep.2019.112216

Journal of Ethnopharmacology

2020

DOI: 10.1016/j.jep.2019.112216

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HPLC-ESI-QqQ based standardization, mutagenic and genotoxic potential of methanol extract of Ziziphus mauritiana Lam leaves

Mohan Kumar Ramar

Yamini Dhayanandamoorthy

Shiyam Sundar Ramachandran

et al.

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Cited by 6 publications

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“…The genus Ziziphus belongs to the family Rhamnaceae and consists of 40 species of spiny shrubs and trees (Owolarafe et al, 2020;Patel et al, 1988). Among these 40 species is Ziziphus mauritiana Lam., which is also known as Indian jujube or ber, and is native to Asia and Africa (Ramar et al, 2020). The two most important horticultural Ziziphus species are Z. mauritiana and Z. jujuba Mill.…”

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confidence: 99%

Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal

Sakhanokho

Islam‐Faridi

Smith

2022

horts

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Ziziphus mauritiana Lam. is a widespread shrub or tree of the Sahel region, where it grows wild and is used for various purposes, including nutrition, medicine, and firewood. Current domestication programs focus on using the local species as rootstock for the improved imported Asian cultivars to provide tolerance to pests and diseases. The plant plays an increasing economic role in the livelihoods of local Sahelian populations, but despite this there is little genetic information about it. The purpose of our study was to determine the genome size estimate and chromosome numbers of Z. mauritiana germplasm collected from eastern Senegal, West Africa. Genome size estimates were determined using flow cytometry, and chromosome count was achieved using chromosome spreads of actively growing root tips. The mean, median, minimum, and maximum genome size estimates (1Cx-DNA) of Z. mauritiana were 418.74 Mb, 417.45 Mb, 410.72 Mb, and 432.12 Mb, respectively. Plants of the germplasm investigated were found to be octoploid with a chromosome number of 2n = 8x = 96. The genetic information gathered in this study can be useful for phylogenetic studies, sequencing projects, and domestication programs that focus on controlled pollination for the development of improved Z. Mauritania cultivars in the Sahel region.

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Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal

Sakhanokho

Islam‐Faridi

Smith

2022

horts

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Phytochemical and chemotaxonomic investigations on the aerial parts of Artemisia halodendron Turcz. ex Bess

Jin

Yang

Xue

et al. 2023

Biochemical Systematics and Ecology

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Ziziphus mauritiana Lam attenuates inflammation via downregulating NFκB pathway in LPS-stimulated RAW 264.7 macrophages & OVA-induced airway inflammation in mice models

Ramar¹,

Henry²,

Ramachandran³

et al. 2022

Journal of Ethnopharmacology

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HPLC-ESI-QqQ based standardization, mutagenic and genotoxic potential of methanol extract of Ziziphus mauritiana Lam leaves

Cited by 6 publications

References 21 publications

Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal

Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal

Phytochemical and chemotaxonomic investigations on the aerial parts of Artemisia halodendron Turcz. ex Bess

Ziziphus mauritiana Lam attenuates inflammation via downregulating NFκB pathway in LPS-stimulated RAW 264.7 macrophages & OVA-induced airway inflammation in mice models

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