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Cited by 297 publications
(236 citation statements)
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References 120 publications
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“…Since the pioneering work of Julius Adler almost 40 years ago (Adler, 1965), genetic, biochemical and biophysical studies of chemotaxis have been focussed mostly on enterobacteria, essentially on Escherichia coli and Salmonella, thus contributing greatly to the goal of ' understanding a simple behaviour at the molecular level ' (Parkinson, 1987). Today, the enterobacterial sensory pathway and all central components of the signal transduction chain as well as interactions between these proteins have been identified (for recent reviews see Bren & Eisenbach, 2000 ;Falke et al, 1997 ;Grebe & Stock, 1998 ;Macnab, 1996). However, many molecular details of receptor function, signal amplification and signal processing, of flagellar motor mechanics and regulation are still not understood.…”
Section: Overviewmentioning
confidence: 99%
“…Since the pioneering work of Julius Adler almost 40 years ago (Adler, 1965), genetic, biochemical and biophysical studies of chemotaxis have been focussed mostly on enterobacteria, essentially on Escherichia coli and Salmonella, thus contributing greatly to the goal of ' understanding a simple behaviour at the molecular level ' (Parkinson, 1987). Today, the enterobacterial sensory pathway and all central components of the signal transduction chain as well as interactions between these proteins have been identified (for recent reviews see Bren & Eisenbach, 2000 ;Falke et al, 1997 ;Grebe & Stock, 1998 ;Macnab, 1996). However, many molecular details of receptor function, signal amplification and signal processing, of flagellar motor mechanics and regulation are still not understood.…”
Section: Overviewmentioning
confidence: 99%
“…While moving along a gradient of a chemoattractant, the intracellular concentration of phosphorylated CheY inside the bacterial cytoplasm decreases. Therefore, the rate of site directed "runs" along the gradient increases [47].…”
Section: Experimental Approachesmentioning
confidence: 99%
“…The methylation of the specific glutamyl-residues on the chemoreceptor signalling domains is a S-adenosylmethionine-consuming process catalysed by CheR [47]. Methylation is triggered by attracting stimuli.…”
Section: Different Mechanisms Of Sensory Adaptationmentioning
confidence: 99%
“…The interest in bacterial chemotaxis is broad. Knowledge is sought of how the bacteria sense chemicals (4,(21)(22)(23), how chemotaxis affects pathogenesis and symbiosis (10,29,57), the role of chemotaxis in the formation and structure of bacterial communities (70), the influence of chemotaxis on oceanic nutrient cycling (8,9,17,75), and the effect of chemotaxis on pollutant biodegradation (43,52,(54)(55)(56).…”
mentioning
confidence: 99%