How Physicians Should Evaluate Dietary Supplements

Glisson, James; Walker, Larry

doi:10.1016/j.amjmed.2009.10.017

Cited by 32 publications

(34 citation statements)

References 13 publications

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“…There is a tremendous potential for the excessive or inappropriate use of these products [22][23][24][25][26][27]. In addition, this may compromised the purchasing of medicines especially where there are high co-payments.…”

Section: Expert Commentarymentioning

confidence: 99%

Over-the-counter medicine and dietary supplement consumption among academic youth in Poland

Bochenek

Godman

Lipowska

et al. 2016

Expert Review of Pharmacoeconomics & Outcomes Research

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This version is available at https://strathprints.strath.ac.uk/55549/ Strathprints is designed to allow users to access the research output of the University of Strathclyde. Unless otherwise explicitly stated on the manuscript, Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. Please check the manuscript for details of any other licences that may have been applied. You may not engage in further distribution of the material for any profitmaking activities or any commercial gain. You may freely distribute both the url (https://strathprints.strath.ac.uk/) and the content of this paper for research or private study, educational, or not-for-profit purposes without prior permission or charge.Any correspondence concerning this service should be sent to the AbstractOver-the-counter (OTC) medicines and dietary supplements are increasingly popular in Poland, potentially improving overall health but also posing a threat to public health. The study goal is to characterize and assess behaviors related to use of OTC medicines and dietary supplements among Polish university students. A questionnaire-based survey was performed with students divided into groups (gender, subjects studied, period of studies). The majority of students declared using the products, significantly more females and younger students in their early years. Females tended to be more attentive to product information. Students with a background in biological or medical sciences were also more attentive and less influenced by advertising. We conclude that the differences between the defined groups of students should be utilized in tailored educational activities, aiming to rationalize high consumption of OTC medicines and dietary supplements. Targeting other, especially poor and less-educated groups, should follow.

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Section: Expert Commentarymentioning

confidence: 99%

Over-the-counter medicine and dietary supplement consumption among academic youth in Poland

Bochenek

Godman

Lipowska

et al. 2016

Expert Review of Pharmacoeconomics & Outcomes Research

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“…Average contents of Ca 344 g*kg were observed in egg shell of Lohmann Brown laying hens (Tůmová et al, 2014). Glisson and Walker (2010) reported that sodium, potassium and chlorides occurs for the most part as free minerals and other minerals are usually bound to proteins and phospholipids. Main factor which affect amount of minerals in eggs is feed.…”

Section: Mineral Composition Of Egg Massmentioning

confidence: 99%

The effect of essential plant oils on mineral composition of egg mass and blood parameters of laying hens

Herkeľ¹,

Gálik²,

Bíro³

et al. 2016

JCEA

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The aim of study was to analyze the dietary effect of pumpkin and flaxseed oils on mineral composition of egg mass and blood parameters of laying hens. At 38 weeks of age, Lohmann Brown Lite hens were housed in three-floor cages, divided into three dietary groups (C-control, E1-pumpkin oil (3%), E2-flaxseed oil (3%)). There were housed six hens in one cage. A total 18 hens were monitored. In the control group hens were fed with standard complete feed mixture for laying hens and in the experimental groups by feed mixtures with supplementation of pumpkin or flaxseed oils. Vitamin E was added into feed mixture in the experimental groups. The experiment lasted 52 days. Twelve eggs from each dietary treatment were randomly selected and analyzed. As regards the mineral composition of eggs, only concentrations of calcium after both oil supplementations and zinc after flaxseed oil supplementation in diet were significantly (P<0.05) higher in yolk. Contents of magnesium in yolk and albumen and phosphorus in albumen were markedly (P<0.05) lower in E1 and E2 compared to the control. Also lower (P<0.05) concentrations of potassium after flaxseed oil supplementation in yolk and zinc after both oil supplementation in albumen compared to the control were found. The amounts of other minerals were relatively balanced among groups. Significant (P<0.05) differences among groups in blood parameters of laying hens were observed in mineral and energy profile. Higher (P<0.05) concentrations of calcium, triglycerides and cholesterol in both experimental groups in comparison with control group were found in blood serum of laying hens. The supplementation of oils in diets of laying hens had not notable (P>0.05) influence on enzymatic and protein profile. AbstraktCieľom práce bolo analyzovať vplyv tekvicového a ľanového oleja na úžitkovosť nosníc a nutričné zloženie konzumných vajec. Do pokusu boli zaradené nosnice hybridu Lohmann Brown Lite vo veku 38 týždňov, ktoré boli rozdelené do troch diétnych skupín (C-kontrola, E1-tekvicový olej (3%), E2-ľanový olej (3%)). Nosnice boli ustajnené v trojetážovej klietkovej technológii (6 zvierat v jednej klietke). Spolu bolo monitorovaných 18 nosníc. V kontrolnej skupine nosnice prijímali štandardnú kompletnú kŕmnu zmes a v experimentálnych skupinách bola táto kŕmna zmes obohatená o prídavok tekvicového alebo ľanového oleja. Do pokusných diét bol pridávaný aj vitamín E. Experiment trval 52 dní. Z každej skupiny bolo náhodne vybraných a analyzovaných 12 vajec. Čo sa týka minerálneho zloženia vajec, preukazne (P<0.05) vyšší obsah vápnika bol zaznamenaný po oboch olejových prídavkoch a preukazne vyšší obsah zinku v skupine s ľanovým olejom v porovnaní s kontrolnou skupinou vo vaječnom žĺtku. Obsahy horčíka v žĺtku a bielku a fosforu v bielku boli preukazne (P<0.05) nižšie v E1 a E2 v porovnaní s kontrolou. Pokles (P<0.05) v koncentrácii draslíka po prídavku ľanového oleja v žĺtku a zinku po pridaní oboch olejov v bielku bol pozorovaný v porovnaní so skupinou bez olejového prídavku. Množstvo os...

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“…Therefore, physicians, pharmacists, nurses, midwifes, and other health care professionals have a critical responsibility assessing the self-care ability of their patients. 70,71 Databases are available for pharmacists with information on action, side effects and toxicities as well as herb-drug interactions. A well known database is the DMDI-ABDA database of the German Institute for Medical Documentation and Information (http://www.…”

Section: Perspectives For a 'Take Actions' Plan Development Of Educatmentioning

confidence: 99%

“…Complex issues persist, which have to be addressed when consulting patients. 9 Dietary supplements are often used by patients at their own discretion without knowledge of and control by their physicians. Patients may anticipate physicians' disapproval of their use, or not realize that it is important for the physician to know what they are taking.…”

Section: Introductionmentioning

confidence: 99%

Self-medication with nutritional supplements and herbal over-thecounter products

Eichhorn

Greten

Efferth

2011

Nat. Prod. Bioprospect.

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Abstract:In recent years, the popularity increased for nutritional supplements and herbal products. Prescription drugs, but not herbal therapies are paid by health insurances. They are sold over-the-counter (OTC) on the patients' own expense. However, there are potential risks of self-medication, e.g. incorrect self-diagnosis, severe adverse reactions, dangerous drug interactions, risk of addiction etc. They are often used by patients at their own discretion without knowledge of and control by their physicians. Certain users are at risk of intoxication. Multiple medications taken by older patients increase the risk for adverse drug reactions, drug-drug interactions, and compliance problems for this age group (polypharmacy). Herbals should be discontinued prior to operations to avoid interactions with anesthetics or anticoagulants. Herbal preparations may also be carcinogenic or interfere with cancer treatments. Pregnant women use various OTC preparations. However, in many cases, it is unclear whether their use is safe for mother or baby. Self-medication with herbals is also largely distributed among anxious and depressive patients, and patients with other conditions and symptoms. The popularity of herbal products has also brought concerns on quality, efficacy and safety. Cases of botanical misidentification, contaminations with heavy metals, pesticides, radioactivity, organic solvents, microbials as well as adulteration with chemical drugs necessitate the establishment of international quality control standards. Hepatotoxic effects have been reported for more than 300 plant species, and some commonly used herbs have been demonstrated to interact with Western medication. Health care professionals have a critical responsibility assessing the self-care ability of their patients. Databases are available for pharmacists with information on action, side effects and toxicities as well as herb-drug interactions. There is a need for established guidelines regarding the correct use of nutritional supplements and herbal OTC preparations (phytovigilance). Physicians, pharmacists, and other health care professionals have to counsel patients and the general public on the benefits and risks associated with herbal drugs. Information centers for consumers and general practitioners are needed, and convincing evidence on safety and efficacy of herbal products has to be demonstrated in placebo-controlled, double blind and randomized clinical trials.

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How Physicians Should Evaluate Dietary Supplements

Cited by 32 publications

References 13 publications

Over-the-counter medicine and dietary supplement consumption among academic youth in Poland

Over-the-counter medicine and dietary supplement consumption among academic youth in Poland

The effect of essential plant oils on mineral composition of egg mass and blood parameters of laying hens

Self-medication with nutritional supplements and herbal over-thecounter products

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