2015
DOI: 10.3109/14756366.2015.1054819
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Abstract: The purpose of this study was to investigate the anti-hyaluronidase activities of honeys from different botanical origins honeys in order to determine their anti-inflammatory properties. The total phenolic contents, total flavonoids and total tannin levels of six types of honey, chestnut, oak, heather, pine, buckwheat and mixed blossom, were determined. Concentrationrelated inhibition values were tested turbidimetrically on bovine testis hyaluronidase (BTHase) as IC 50 (mg/mL). All honeys exhibited various con… Show more

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Cited by 22 publications
(30 citation statements)
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“…Several injections were realized and successive polar/less polar fractions were respectively pulled together to recover enough material to assess their bioactivities the same way as the one of Oak1. Positive relationships were also observed between anti-hyaluronidase activity and phenolic content in the cases of fractions Oak1_F4 and Oak1_F5, as well as between anti-elastase activity and flavonoid content in the cases of fraction Oak1_F3 and to a lesser extent, of fraction Oak1_F4, as previously stated in the literature [52,54].…”
Section: Fractionation Schemesupporting
confidence: 71%
“…Several injections were realized and successive polar/less polar fractions were respectively pulled together to recover enough material to assess their bioactivities the same way as the one of Oak1. Positive relationships were also observed between anti-hyaluronidase activity and phenolic content in the cases of fractions Oak1_F4 and Oak1_F5, as well as between anti-elastase activity and flavonoid content in the cases of fraction Oak1_F3 and to a lesser extent, of fraction Oak1_F4, as previously stated in the literature [52,54].…”
Section: Fractionation Schemesupporting
confidence: 71%
“…Novel natural inhibitors are needed in many areas to contribute to the controlled inhibition of hyaluronidase. However, hyaluronidase inhibitors have also led to new therapeutic concepts in pathophysiological conditions that associated with the hyaluronan-hyaluronidase system 9 . Chestnut honeys inhibited the hyaluronidase at varying IC 50 values (76 to 129 mg/mL), (Table 1) and this inhibition was associated with their unifloral character.…”
Section: Resultsmentioning
confidence: 99%
“…Ureases that produce excess ammonium are also involved in the development of urolithiasis, pyelonephritis, hepatic encephalopathy, hepatic coma urolithiasis and urinary catheter encrustation in humans and animals 9 . The urease inhibition is also important to deal with Helicobacter pylori in gastric diseases 9 .…”
Section: Resultsmentioning
confidence: 99%
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