Hollow Co-CeO2@PEG nanospheres: Ultrasound enhanced cascade-nanozyme for synergetic anticancer

Defective S‐TiO2−x/CeO2 Heterojunction for Mutual Reinforcing Chemodynamic/Sonocatalytic Antibacterial Therapy and Sonoelectric/Ion‐Activated Bone Regeneration

“…Compared with TiO 2 , TC showed some new peaks, which are located at 28.54 o (111), 33.07 o (200), and 47.48 o (220), corresponding with the lattice parameters of CeO 2 . [22] The characteristic diffraction peaks of both S-TiO 2-X and CeO 2 appear on S-TiO 2-X /CeO 2 , demonstrating the successful synthesis of S-TiO 2-x/ CeO 2 heterojunction materials. A Raman spectrum (Figure 2e) was used to further investigate the chemical structure phases of S-TiO 2-X /CeO 2 .…”

“…Unfortunately, doped titanium dioxide electron and hole pairs still recombine rapidly. [20][21][22] The construction of heterojunctions is currently the most important strategy to inhibit the separation of electron and hole pairs. As a semiconductor material, CeO 2 has good electron-conducting ability.…”

Nanozyme: a rising star for cancer therapy

“…65 Lin's group synthesized Co-CeO 2 @PEG hollow nanospheres. 66 Co-doping provided more oxygen vacancies and narrowed the band gap, which optimized the separation of the electron-hole and the transfer of carriers. Moreover, the hollow structure allows the introduction of additional cavitation nuclei, promoting cavitation effects and ROS production.…”

The rational design of nanozymes for imaging-monitored cancer therapy

“…For POD-like and CAT-like nanozymes, the key to tumor therapy is the concentration of intratumoral H 2 O 2 . 119–123 Under the catalysis of nanomaterials, the excess H 2 O 2 in tumor areas can be transformed into hydroxyl radicals (˙OH) or O 2 higher cytotoxicity to kill tumor cells directly or treat cancers along with other treatments (photodynamic, etc. ) by supplementing local oxygen to boost the therapeutic effects.…”