HLA markers and lymphocytotoxins in lichen planus

Saurat, J. H.

doi:10.1001/archderm.113.12.1719

Cited by 13 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…HLA-A3 was found in 54% of a group of 57 nonfamilial LP patients compared with a control fre quency of 30% [18]. Subsequent studies, however, did not demonstrate statistically significant differences from con trols [ 19,20] and failed to find this HLA in FLP [8,16]. In a group of 72 nonfamilial LP patients [21] HLA DR1, which is in linkage disequilibrium with A3, was found to be more frequent (56%) compared with normal controls (25%).…”

Section: Discussionmentioning

confidence: 91%

Familial Lichen planus

Katzenelson

Lotem²,

Sandbank³

1990

Dermatology

View full text Add to dashboard Cite

Familial lichen planus (FLP) was observed to have developed within a period of 3 years in 2 sisters as well as in the son of one of the women. In contrast to typical FLP, the eruption was generalized in only 1 of these patients; no atypical forms were observed; the response to topical treatment with steroids was rapid, and the relapses were few and mild. Previous reports of familial cases of lichen planus as well as the long interval between onset of the disease in the affected members of the family speak in favor of a genetic predisposition. HLA typing revealed HLA DR in all 3 patients. There was no increased incidence of HLA B7, HLA A3 or HLA A28.

show abstract

Section: Discussionmentioning

confidence: 91%

Familial Lichen planus

Katzenelson

Lotem²,

Sandbank³

1990

Dermatology

View full text Add to dashboard Cite

show abstract

“…B 7 in familial LP (20), and B 8 in OLP (21). On the other hand, other studies reported no stich associations (22)(23)(24). Becker (1985) studied HLA-DR 1 to DR 7 antigens as well as Class 1 antigens in 21 Germans with OLP.…”

Section: Discussionmentioning

confidence: 91%

“…In the ease of LP, some reports suggested the possible association of HLA Class 1 antigens (17)(18)(19)(20)(21), but tbe other studies indieated no associations (22)(23)(24).…”

mentioning

confidence: 99%

Analysis of HLA antigens in Japanese with oral lichen planus

Watanabe

Ohishi

Tanaka

et al. 1986

J Oral Pathology Medicine

View full text Add to dashboard Cite

of HLA antigens in Japanese with oral liehen planus. . 1 Oral Pathol 1986: 15: 529-533. Analysis of HLA antigens was performed in 42 .lapanese patients with oral lichen planus (OLP). There were no significant differences in the frequency of HLA-A, B, C antigens between OLP-patients and control subjects, although a decreasing trend in the frequency of Bw 52 and an increasing trend in that of Bw 61 and Cw 3 was noted. Among the HLA-DR and DO antigens studied, the frequency of DRw 9 was significantly increased (Pc<().()5, RR = 3.3) and the relative risk was inereased (RR = 6.()) when DRw 9 was earried on as a Bw 61/DRw 9 haplotype. Our results suggest that HLA-associated genetic factors play a role to some extent in the development of OLP.

show abstract

“…When the available data on HLA tissue typing of patients with lichen planus are pooled ( the group of patients of Saurat et al ( 11), those of Lowe, Cud worth & Woodrow (7), and the group presented here) a total of I 89 patients and 2 858 controls have been examined (Table IV). The most marked devia tions were seen for HLA-A 3 (present in 33-54 % of the patients and 26-30 % of the controls).…”

Section: Resultsmentioning

confidence: 99%

HLA antigens in patients with lichen planus

Veien¹,

Risum²,

Jørgensen³

et al. 1979

Acta Derm Venereol

View full text Add to dashboard Cite

HLA-ABC antigens were determined in 89 patients with biopsy-confirmed lichen planus, and the HLA antigen frequencies were compared with those in 1967 controls. The younger patients were predominantly male, the older patients predominantly female. No significant association was found between HLA types and lichen planus in this study. A slightly greater incidence of HLA-A3 and B5 antigens was seen, but this increased frequency was not as pronounced as reported by others. When combined, available data on HLA and lichen planus indicate a slightly, but significantly, increased frequency of HLA-A3. None of the HLA antigens known to be associated with insulin-dependent diabetes are associated with lichen planus.

show abstract

HLA markers and lymphocytotoxins in lichen planus

Cited by 13 publications

References 0 publications

Familial Lichen planus

Familial Lichen planus

Analysis of HLA antigens in Japanese with oral lichen planus

HLA antigens in patients with lichen planus

Contact Info

Product

Resources

About