HL‐A Antigens in Leprosy

Abstract

HL—A phenotype frequencies were studied in 30 patients with leprosy and in 149 healthy controls. Leprosy patients had a significantly higher frequency of HL—A14. In addition, a majority of the HL—A14 patients gave a negative response to leproma antigen using the Mitsuda test.

HLA and Leprosy in Chinese

“…HLA associations in leprosy have been shown in some studies (Thorsbyet al 1973, Kreisler et al 1974, Takata e t al. 1978 but not in others (Reis et al 1974, Dasgupta e t al.…”

Geography and Race in Uveitis

“…HLA associations of leprosy have been shown in some studies (Thorsby et al 1973;Kreisler et al 1974;Tagawa et al 1977;Takata et al 1978) but not in others (Reis et al 1974;Dasqupta et al 1975;Smith et al 1975;Nocera 1980;De VrieS et al 1980: Bale et al 1982 and those studies which suggest a relationship are not in agreement. It is only in regard to tuberculoid leprosy that HLA encoded genetic factors (HLA-DR2) have been firmly established (VanEden et al 1983).…”

Posible origen de la inmunodeficiencia en la hanseniasis virchowiana

“…La primera de las posibilidades expuestas en nuestra hipótesis trabajo encuentra como principal obstáculo los contradictorios resultados obtenidos por diversos investigadores, al estudiar la relación del CMH con las formas clinicas de la hanseniasis (21,33). La mayoría de los autores refieren no haber hallado diferencias significativas en los halotipos de pacientes virchowianos, tuberculoides y testigos sanos (7,45) lo cual se contradite con las observaciones de De Vries.…”