HIV-Associated pruritus

Eosinophilic pustular folliculitis: A 40 year retrospect

“…4,15 Rather than clusters of large pustules, IS-EPF may have only discrete erythematous raised follicular papules, which are often largely excoriated and edematous. 11,16 As a result, diagnosis is more difficult and often requires multiple biopsy specimens before adequate histologic information is obtained. The CD4 cell count tends to be less than 250 to 300 cells/mL.…”

Infectious differential diagnosis of chronic generalized pruritus without primary cutaneous lesions: a review of the literature

“…Chronic pruritus has been – and still is – a common symptom in patients with human immunodeficiency virus (HIV) even in the new era of highly active antiretroviral therapy (HAART) and combination antiretroviral therapy (cART) . A study in the United States in 2012 has reported a 45% prevalence rate in 201 HIV‐infected patients, an estimate which is close to the 31% documented by a study in Spain on 303 HIV‐infected patients in 2003 …”

“…A range of primary skin disorders (such as xerosis, atopic dermatitis, seborrheic dermatitis, psoriasis, infections like scabies or dermatophyte infections, etc.) may be the etiology of pruritus or might be the reason for exacerbation, relapse, or more severe manifestations of an underlying skin disorder . Chronic pruritus may also be associated with systemic disorders in HIV‐infected patients (e.g.…”

“…Chronic pruritus may also be associated with systemic disorders in HIV‐infected patients (e.g. lymphomas, chronic renal diseases, diabetes mellitus and other endocrinopathies, hepatic diseases like cholestasis, and drug reactions) …”