Histopathology of Deafness Due to Postnatal Viral Disease

Late Sequelae of Cochlear Infection

“…In the worst cases Reissner's membrane formed a cyst within the cochlear duct. This degenerative pattern is similar to that described for humans following viral labyrinthitis 11 . Khetarpal et al 12 reported a decreased cellularity of the spiral limbus in the human temporal bone following viral labyrinthitis that was seen in some instances in the guinea pig cochleas.…”

Cochlear implants for mumps deafness: two paediatric cases

“…However, the pathology findings report by Lindsay 11 , have also suggested the likelihood of a secondary cochlear disorder by postmeningitic inflammation. It is generally thought that meningitis brought about by the mumps virus spreads to the auditory nerve in the columella cochleae, and that the inflammation extends to the peri-lymphatic space through the cochlear aqueduct.…”

“…• Individuals with bilateral mumps deafness have been considered good candidates for cochlear implants • We cannot predict the hearing prognosis before a cochlear implant procedure • A thorough informed consent should be discussed with patients and the parents of minors, especially in cases with risk factors such as vestibular or meningitic symptoms However, the pathology findings report by Lindsay 11 , have also suggested the likelihood of a secondary cochlear disorder by postmeningitic inflammation. It is generally thought that meningitis brought about by the mumps virus spreads to the auditory nerve in the columella cochleae, and that the inflammation extends to the peri-lymphatic space through the cochlear aqueduct.…”

The clinical features and prognosis of mumps-associated hearing loss: a retrospective, multi-institutional investigation in Japan

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