“…However, absolute ethanol is highly corrosive, thus easily causing tissue necrosis. 23 Therefore, bleomycin was used as the primary sclerosant in this study. By binding to the DNA of lymphatic endothelial cells (LECs), bleomycin inhibited DNA synthesis, cut DNA strands, damaged endothelial cells, thickened walls, narrowed the lumen, and eventually caused focal atrophy.…”