Histology and cytochemistry of human skin. XXXVI. The nose and lips

Abstract

The skin of the nose is characterized by often conspicuously dilated openings of the ducts of many subaceous follicles. Histological sections are dominated by gigantic sebaceous follicles, but there are also numerous vellus hairs with small sebaceous glands. All hair follicles on the surface of the nose and in the vestibule are completely invested with nerve end organs. In the vestibule, the glabrous upper surface has intraepidermal nerves and a few mucocutaneous end organs. the vermillion zone of the lip, which seperates the skin of the external lip and the mucosa of the inner lip, is keratinizing glabrous epithelium, often with numerous sebaceous glands in the upperlip. The transitional area between the keratinizing epithelium of the vermillion and the nonkeratinizing epithelium of the labial mucosa is abundantly supplied with mucocutaneous end organs, with only a few in the labial mucosa. The mucoserous glands of the labial mucosa are richly innervated.

Histological changes at the commissure of the lip on approaching from its cutaneous to the mucosa region in males

“…In the microscopic study of Dimond and Montagna on 4 males (aged 20, 22, 25, and 65 years) and 1 female (aged 30 years) found the dermis of the vermillion border to be 0.5 mm thick, and the lamina propria of the mucosa was found to be similar in thickness to the dermis of its cutaneous part. [ 13 ] Data were found to be approximated to our findings. However, the thickness of the lamina propria was not as thick as the dermis of the skin in our observations.…”

“…The study found that the epithelium of the labial mucosa measured 0.7 mm thick and its lamina propria was found similar in thickness to the dermis of cutaneous part of the lip. [ 13 ] Satheer et al . (2011) concluded in their review article about the human lip that the mean epithelial thickness of the skin, vermillion zone, and oral mucosa was 46 ∝m, 97 ∝m, and 218 ∝m, respectively.…”

Functional map and age‐related differences in the human face: nonimmunologic contact urticaria induced by hexyl nicotinate

“…This difference between the 2 age groups might be partly explained by the enlargement of the sebaceous glands in the elderly (11). The ultra violet A (UVA) has been reported to induce sebaceous gland hyperplasia (12) that might lead to the enlargement of the sebaceous glands in the face when compared to other areas (13,14) and in the elderly when compared to the younger subjects (11,15).…”

Epidermis as a Platform for Bacterial Transmission

“…It seems clear that there is no sharp border but rather a gradient of conditions, likely dependent on physical variables such as humidity and temperature. These transitional areas are obvious in the lips, where we observe the non-keratinized epithelium of the labial mucosa transitioning to the buccal mucosa, with surfaces changing with age ( 9 – 11 ). Similar “borders” occur at the eyes, rectum, and vaginal mucosa and the neighboring keratinized epidermis.…”