“…In addition, the impact of this line of biotherapy on the enteric and cerebral inflammatory microenvironments is another need for research. The World Health Organization and Food and Agriculture Organization defined probiotics as bacteria that when applied in satisfactory quantities improve the fitness of the host ( Reid, 2005 ) being related to the host metabolism ( El Saftawy et al, 2021a , El Saftawy et al, 2021b ). These bacteria can be viable ( Reid, 2005 ) or dead ( Taverniti and Guglielmetti, 2011 ).…”