Histologic Classification of Tumors of the Central Nervous System

A brief history of ependymoma

“…Throughout the first half of the 20th century, a lively debate concerning the optimal classification of ependymoma remained ongoing. For instance, the French physicians Roussy and Oberling proposed an alternative classification system, in which ependymomas were grouped together with choroid plexus carcinoma and subsequently divided into the three subgroups “ependymocytoma,” “ependymomaglioma,” and “ependymoblastoma.” 34 , 35 In 1932, Kernohan described for the first time myxopapillary ependymoma of the spinal cord, and in 1945, Scheinker identified subependymomas as a distinct variant from other ependymal tumors. 36 , 37 Both entities are still used until today.…”

A brief history of ependymoma

“…Throughout the first half of the 20th century, a lively debate concerning the optimal classification of ependymoma remained ongoing. For instance, the French physicians Roussy and Oberling proposed an alternative classification system, in which ependymomas were grouped together with choroid plexus carcinoma and subsequently divided into the three subgroups “ependymocytoma,” “ependymomaglioma,” and “ependymoblastoma.” 34 , 35 In 1932, Kernohan described for the first time myxopapillary ependymoma of the spinal cord, and in 1945, Scheinker identified subependymomas as a distinct variant from other ependymal tumors. 36 , 37 Both entities are still used until today.…”

Pío del Río Ortega: A Pioneer in the Pathology of Central Nervous System Tumors

“…The histogenetic and embryological approach adopted by Ribbert was modified by the cellular approach espoused mainly by Río Hortega. The contributions of the French school (Lhermitte and Dumas, 1916 ; Cornil, 1924 ; Roussy and Oberling, 1932 ) around the 1920 made it possible to distinguish between fibrillary astrocytoma, four subgroups of non-fibrillary glioma (round, spindle-shaped, polymorphic, and ameboid cells), glioblastoma, and spongioblastoma. The classification included ependymomas with choroid plexus tumors, which were separate from the other gliomas.…”

Current and Evolving Knowledge of Prognostic Factors for Pediatric Ependymomas

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A brief history of ependymoma

“…Throughout the first half of the 20th century, a lively debate concerning the optimal classification of ependymoma remained ongoing. For instance, the French physicians Roussy and Oberling proposed an alternative classification system, in which ependymomas were grouped together with choroid plexus carcinoma and subsequently divided into the three subgroups “ependymocytoma,” “ependymomaglioma,” and “ependymoblastoma.” 34 , 35 In 1932, Kernohan described for the first time myxopapillary ependymoma of the spinal cord, and in 1945, Scheinker identified subependymomas as a distinct variant from other ependymal tumors. 36 , 37 Both entities are still used until today.…”

Pío del Río Ortega: A Pioneer in the Pathology of Central Nervous System Tumors

“…The histogenetic and embryological approach adopted by Ribbert was modified by the cellular approach espoused mainly by Río Hortega. The contributions of the French school (Lhermitte and Dumas, 1916 ; Cornil, 1924 ; Roussy and Oberling, 1932 ) around the 1920 made it possible to distinguish between fibrillary astrocytoma, four subgroups of non-fibrillary glioma (round, spindle-shaped, polymorphic, and ameboid cells), glioblastoma, and spongioblastoma. The classification included ependymomas with choroid plexus tumors, which were separate from the other gliomas.…”

Current and Evolving Knowledge of Prognostic Factors for Pediatric Ependymomas

“……”

A brief history of ependymoma

“…Throughout the first half of the 20th century, a lively debate concerning the optimal classification of ependymoma remained ongoing. For instance, the French physicians Roussy and Oberling proposed an alternative classification system, in which ependymomas were grouped together with choroid plexus carcinoma and subsequently divided into the three subgroups “ependymocytoma,” “ependymomaglioma,” and “ependymoblastoma.” 34 , 35 In 1932, Kernohan described for the first time myxopapillary ependymoma of the spinal cord, and in 1945, Scheinker identified subependymomas as a distinct variant from other ependymal tumors. 36 , 37 Both entities are still used until today.…”

Pío del Río Ortega: A Pioneer in the Pathology of Central Nervous System Tumors

“…The histogenetic and embryological approach adopted by Ribbert was modified by the cellular approach espoused mainly by Río Hortega. The contributions of the French school (Lhermitte and Dumas, 1916 ; Cornil, 1924 ; Roussy and Oberling, 1932 ) around the 1920 made it possible to distinguish between fibrillary astrocytoma, four subgroups of non-fibrillary glioma (round, spindle-shaped, polymorphic, and ameboid cells), glioblastoma, and spongioblastoma. The classification included ependymomas with choroid plexus tumors, which were separate from the other gliomas.…”

Current and Evolving Knowledge of Prognostic Factors for Pediatric Ependymomas

“……”