Histologic artifacts of benign pigmented nevi

Benign melanocytic lesions with emphasis on melanocytic nevi – A histomorphological analysis

“…3 We did not find any site-specific unusual histopathological feature as mentioned by other authors except in 1 case from conjunctiva which showed worrisome atypia. 3,15 Stoma showed secondary changes including artifactual cleft formation in 24 cases as also mentioned by Sagebiel RW et al 16 Association of other secondary lesions with nevus are known. 3 We have seen 1 case each of epithelial inclusion cyst and basal cell carcinoma as also noted by other authors.…”

The Pseudoinflammatory Pattern Revisited

“…During my time in New York, Scott would often point out “the pseudovascular spaces of Sagebiel” while we were viewing intradermal nevi. The eponym commemorated a 1972 study in which Sagebiel discovered a pseudovascular (his term) pattern in 10% of 350 melanocytic nevi [9]. This classic paper illustrated the separation of nevus cells away from the adjacent stroma and from each other, resulting in clefts that simulated vessels.…”