Abstract:Seven groups of 84 male white rats ( Rattus norvegicus) were exposed to lead acetate (0, 0.125, 0.25, 0.5, 1.0, 2.0, and 4% for 1 to 5 months) in drinking water to investigate possible histochemical changes in the activity of renal phosphatases due to lead intoxication. In comparison with respective control rats, chronic exposure to subtoxic doses of lead increased the activities of acid-, neutral-, alkaline-, and membrane-bound Na+-K+ adenosine triphosphatase and glucose-6-phosphatase. In contrast, significan… Show more
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