Hippocampal Sclerosis and Human Memory

The Relationship Between Quantitative MRI and Neuropsychological Functioning in Temporal Lobe Epilepsy

“…These findings are consistent with a number of reports, suggesting a role for the left hippocampus in prose recall tasks (21,32,33,36,45) and support the contention of Zola Morgan and Squire (63) that the hippocampus has a role in initial learning in order to facilitate consolidation into long-term store, because impairment in the ability to consolidate material results in impaired episodic memory manifested behaviourally as an increased rate of forgetting. These memory deficits were evident in our LHS group on tests involving the learning and recall of verbal material, and in our RHS group in tests involving visual material.…”

The Relationship Between Quantitative MRI and Neuropsychological Functioning in Temporal Lobe Epilepsy

“…These findings are consistent with a number of reports, suggesting a role for the left hippocampus in prose recall tasks (21,32,33,36,45) and support the contention of Zola Morgan and Squire (63) that the hippocampus has a role in initial learning in order to facilitate consolidation into long-term store, because impairment in the ability to consolidate material results in impaired episodic memory manifested behaviourally as an increased rate of forgetting. These memory deficits were evident in our LHS group on tests involving the learning and recall of verbal material, and in our RHS group in tests involving visual material.…”

Is the Right Amygdala Involved in Visuospatial Memory? Evidence from MRI Volumetric Measures

“…The fact that the delayed response constituted the only sensitive measure of hippocampal integrity corroborates a previous conclusion drawn by Miller et al [1993]. A group of TLE patients who underwent the WMS and Rey Complex Figure as part of a presurgical procedure were subsequently divided into two groups depending on the presence or absence of HS determined histologically.…”

Typical asymmetry in the hemispheric activation during an fMRI verbal comprehension paradigm is related to better performance in verbal and non-verbal tasks in patients with epilepsy

“…fMRI activation pattern had implications on cognitive performance: patients with typical hemispheric asymmetry perform better in the digit symbol task and in verbal learning in the total sample and in the subgroup of patients with TLE. As expected, in this subgroup, patients with HS had worse performance in verbal memory than those without HS ( Miller et al, 1993 ).…”

The Relationship Between Quantitative MRI and Neuropsychological Functioning in Temporal Lobe Epilepsy

“…These findings are consistent with a number of reports, suggesting a role for the left hippocampus in prose recall tasks (21,32,33,36,45) and support the contention of Zola Morgan and Squire (63) that the hippocampus has a role in initial learning in order to facilitate consolidation into long-term store, because impairment in the ability to consolidate material results in impaired episodic memory manifested behaviourally as an increased rate of forgetting. These memory deficits were evident in our LHS group on tests involving the learning and recall of verbal material, and in our RHS group in tests involving visual material.…”

Is the Right Amygdala Involved in Visuospatial Memory? Evidence from MRI Volumetric Measures

“…The fact that the delayed response constituted the only sensitive measure of hippocampal integrity corroborates a previous conclusion drawn by Miller et al [1993]. A group of TLE patients who underwent the WMS and Rey Complex Figure as part of a presurgical procedure were subsequently divided into two groups depending on the presence or absence of HS determined histologically.…”

Typical asymmetry in the hemispheric activation during an fMRI verbal comprehension paradigm is related to better performance in verbal and non-verbal tasks in patients with epilepsy

“…fMRI activation pattern had implications on cognitive performance: patients with typical hemispheric asymmetry perform better in the digit symbol task and in verbal learning in the total sample and in the subgroup of patients with TLE. As expected, in this subgroup, patients with HS had worse performance in verbal memory than those without HS ( Miller et al, 1993 ).…”

The Relationship Between Quantitative MRI and Neuropsychological Functioning in Temporal Lobe Epilepsy

“…These findings are consistent with a number of reports, suggesting a role for the left hippocampus in prose recall tasks (21,32,33,36,45) and support the contention of Zola Morgan and Squire (63) that the hippocampus has a role in initial learning in order to facilitate consolidation into long-term store, because impairment in the ability to consolidate material results in impaired episodic memory manifested behaviourally as an increased rate of forgetting. These memory deficits were evident in our LHS group on tests involving the learning and recall of verbal material, and in our RHS group in tests involving visual material.…”

Is the Right Amygdala Involved in Visuospatial Memory? Evidence from MRI Volumetric Measures

“…The fact that the delayed response constituted the only sensitive measure of hippocampal integrity corroborates a previous conclusion drawn by Miller et al [1993]. A group of TLE patients who underwent the WMS and Rey Complex Figure as part of a presurgical procedure were subsequently divided into two groups depending on the presence or absence of HS determined histologically.…”

Typical asymmetry in the hemispheric activation during an fMRI verbal comprehension paradigm is related to better performance in verbal and non-verbal tasks in patients with epilepsy

“…fMRI activation pattern had implications on cognitive performance: patients with typical hemispheric asymmetry perform better in the digit symbol task and in verbal learning in the total sample and in the subgroup of patients with TLE. As expected, in this subgroup, patients with HS had worse performance in verbal memory than those without HS ( Miller et al, 1993 ).…”