Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren)

Remschmidt, Cornelius; Harder, Thomas; Wichmann, Ole; Garbe, Edeltraut; Ledig, Thomas; Terhardt, Martin; Wicker, Sabine; Zepp, Fred; Mertens, Thomas

doi:10.1007/s00103-016-2467-8

Cited by 7 publications

(7 citation statements)

References 95 publications

(35 reference statements)

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“…In Germany, the current influenza immunization recommendation issued by the Standing Committee on Vaccination (STIKO) focuses on individuals aged ≥60 years, individuals with underlying chronic conditions, pregnant women, and healthcare workers 6 . It is especially important to vaccinate those with chronic conditions because vaccination has been associated with improved clinical outcomes among this population, particularly individuals with chronic respiratory disease and cardiovascular disease 7,8 . Currently, available information on influenza VCRs for Germany is limited since published evidence does not always include a detailed breakdown by age and/or risk status.…”

Section: Introductionmentioning

confidence: 99%

“…6 It is especially important to vaccinate those with chronic conditions because vaccination has been associated with improved clinical outcomes among this population, particularly individuals with chronic respiratory disease and cardiovascular disease. 7 , 8 Currently, available information on influenza VCRs for Germany is limited since published evidence does not always include a detailed breakdown by age and/or risk status. Furthermore, large parts of the official VCR surveillance by the Robert Koch Institute (RKI) are only reported graphically.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of chronic conditions and influenza vaccination coverage rates in Germany: Results of a health insurance claims data analysis

Damm

Krefft

Ahlers

et al. 2022

Influenza Resp Viruses

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Background The significant annual burden caused by seasonal influenza has led to global calls for increased influenza vaccination coverage rates (VCRs). We aimed to estimate the proportion of the German population at high risk of serious illness from influenza due to chronic conditions and to estimate age‐specific VCRs of people with/without chronic conditions. Methods Using health insurance claims data covering nine influenza seasons (2010–2019), we assessed up to 7 million insured individuals per season across all German regions. Individuals were classified according to age and presence of chronic health conditions. VCRs were estimated using outpatient healthcare utilization documentation. Results In the 2018–2019 influenza season, 47.3% of individuals had ≥1 chronic condition. Most common were circulatory disorders, accounting for more than a third of individuals with ≥1 condition. Prevalence of chronic diseases, and therefore the proportion of high‐risk individuals, increased slightly over time across most age groups. A downward trend in influenza VCRs was observed in all age groups until the 2017–2018 season, followed by a noticeable increase in the 2018–2019 season. Highest VCRs occurred among individuals of ≥60 years, with a 38.5% VCR for this age group in the 2018–2019 season. Several factors, including age, chronic condition type, and geographical location, affected VCRs. Conclusions Influenza VCRs in individuals at high risk of severe complications from influenza infection are insufficient. Our results suggest that intensified public health efforts are necessary to reach the World Health Organization vaccination coverage target of 75%.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence of chronic conditions and influenza vaccination coverage rates in Germany: Results of a health insurance claims data analysis

Damm

Krefft

Ahlers

et al. 2022

Influenza Resp Viruses

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“…Infants are also at increased risk for severe disease and complications such as otitis media and pneumonia [2]. Therefore, in 2010, the German Standing Committee on Vaccination (STIKO) recommended influenza vaccination for pregnant women from the second trimester of pregnancy, or in case of an underlying chronic disease, from the first trimester onwards [2, 8], with the goal of protecting mothers as well as infants. Influenza vaccines are not licensed for infants until 6 months of age.…”

Section: Introductionmentioning

confidence: 99%

Influenza and pertussis vaccination during pregnancy – attitudes, practices and barriers in gynaecological practices in Germany

Böhm

Röbl-Mathieu

Scheele³

et al. 2019

BMC Health Serv Res

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Background In Germany, antenatal influenza vaccination is recommended since 2010, but uptake remains low. Several countries recently introduced antenatal pertussis vaccination, which is currently under consideration in Germany. We conducted a survey among gynaecologists on attitudes, practices and barriers regarding influenza and pertussis vaccination during pregnancy. Methods Gynaecologists were invited to complete a pre-tested, 24-item questionnaire published in the German Professional Association of Gynaecologists’ journal in September 2017 within 2 months. Associations between variables were examined using Chi-Squared, Fischer’s Exact or t-tests. Variables associated with gynaecologists’ self-reported implementation of vaccination in pregnant women were identified using univariate and multivariate logistic regression analyses. Results Of 867 participants (response 11%), 91.4 and 59.4% reported currently vaccinating pregnant women against influenza and pertussis, respectively. Gynaecologists who reported obtaining annual influenza vaccination and actively informing their patients about these vaccinations were significantly more likely to vaccinate pregnant women against influenza (96.5% vs. 65.7 and 95.1% vs. 62.2%) and pertussis (63.1% vs. 44.3 and 82.4% vs. 12.9%). Performing influenza vaccination was least likely among gynaecologists who perceived logistical difficulties as a vaccination barrier (35.9%), while pertussis vaccination was least likely if the lacking official recommendation (32.0%), logistical difficulties (27.1%), safety concerns (17.5%) and limited vaccine effectiveness (11.1%) were perceived as barriers. Of participants not yet vaccinating pregnant women against pertussis, 86.5% reported they would follow an official recommendation. Including vaccination recommendations in the maternity record (95.2%) and informing the public (88.7%) and health care professionals (86.6%) were considered the most suitable measures to achieve high pertussis vaccination coverage. Conclusions The large proportion reporting performance of influenza vaccination during pregnancy and high acceptance of a potential recommendation for pertussis vaccination reflected positive attitudes towards vaccination among participants. However, factors associated with failure to vaccinate may be more prevalent among non-participants. Results suggest that gynaecologists’ confidence in vaccination is crucial for implementing vaccination in pregnancy. Thus, doubts on vaccine effectiveness and safety should be allayed among gynaecologists and pregnant women via various communication channels, and solutions for logistical barriers sought. Including antenatal vaccination recommendations in the maternity record would serve as an important reminder for both groups. Electronic supplementary material The online version of this article (10.1186/s12913-019-4437-y) contains supplementary material, which is avail...

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“…The sustainable reduction of tobacco consumption is therefore an important goal in terms of preventing lung cancer and COPD as well as other chronic diseases. In addition, some of the burden of disease and premature mortality associated with acute respiratory infections could be avoided by vaccination (influenza and pneumococcal vaccination) [ 114 , 115 ]. This is particularly the case among elderly patients with multiple chronic diseases, as they are significantly more likely to suffer from a severe illness which could even have a fatal outcome [ 114 ].…”

Section: Discussionmentioning

confidence: 99%

Time trends in incidence and mortality of respiratory diseases of high public health relevance in Germany

Steppuhn

Buda

Wienecke

et al. 2017

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Respiratory diseases are major causes of disease burden and mortality throughout the world. In Germany, alongside acute respiratory infections (ARI), chronic lung diseases – including lung cancer, chronic obstructive pulmonary disease (COPD), and asthma – are of particular socioeconomic importance. ARI incidence rates differ significantly according to age, season and year. They are recorded as weekly consultation rates as reported by selected outpatient and inpatient care facilities. Between 2009 and 2016, the highest incidence rates of severe acute respiratory infection (SARI) were recorded among young children in outpatient (9.4%) and inpatient (0.2%) care. Mortality rates for ARI are also subject to seasonal and annual fluctuations. However, the official statistics on causes of death, which lead to estimates of more than 17,000 annual deaths, provide an inadequate measure of death rates because chronic underlying illnesses are often recorded as the cause of death rather than a more recently acquired acute infection. Therefore, the excess mortality caused by ARI needs to be assessed in the context of influenza outbreaks. Regarding lung cancer, COPD and asthma, the long-term time trends in disease incidence and mortality rates are of particular interest from a health policy perspective. Analyses of data from the official statistics on causes of death for the years 1998 through 2015 show that mortality rates for lung cancer and COPD decreased on average by 1.8% and 1.1% per year respectively, among men, whereas among women they increased by 2.5% (lung cancer) and 2.3% (COPD) annually. Nevertheless, more men than women died of lung cancer or COPD in 2015 in Germany: 29,378 men and 15,881 women died from lung cancer, and 17,300 men and 13,773 women died from COPD. During the same period, the asthma mortality rates decreased on average by 8.3% annually among women and by 11.2% annually among men, and the absolute number of deaths came down to 659 among women and 393 among men. Lung cancer incidence rates have been at similar levels as lung cancer death rates since 1998. No such data are available on time trends in COPD or asthma incidence rates. Coordinated surveillance of respiratory diseases needs to be expanded within the framework of international action plans for disease prevention.

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Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren)

Cited by 7 publications

References 95 publications

Prevalence of chronic conditions and influenza vaccination coverage rates in Germany: Results of a health insurance claims data analysis

Prevalence of chronic conditions and influenza vaccination coverage rates in Germany: Results of a health insurance claims data analysis

Influenza and pertussis vaccination during pregnancy – attitudes, practices and barriers in gynaecological practices in Germany

Time trends in incidence and mortality of respiratory diseases of high public health relevance in Germany

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