Highly Sensitive Detection of Amoxicillin Based on Gold Nanoparticle-Modified ITO Electrode

Molecularly imprinted polymer grown on multiwalled carbon nanotube surface for the sensitive electrochemical determination of amoxicillin

“…At present, a number of analytical methods were used to determinate AMOX, such as spectroscopy [5,6], chromatography [7,8], surface plasmon resonance (SPR) [9] and electrochemical method [10][11][12][13][14][15][16]. Generally, molecularly imprinted polymer (MIP) was used as a recognition receptor to enhance the selectivity and/or sensitivity for these methods [17][18][19].…”

“…Yola et al applied MIP to prepare a SPR sensor for the sensitive determination of AMOX [9]. In addition, several modified electrodes were reported to detect its residue based on different voltammetric methods such as cyclic voltammetry [10,11], square wave voltammetry [12], chronoamperometry [13,15] and differential pulse voltammetry [14,16], including multiwalled carbon nanotube (MWCNTs) [11], MWCNTs/FeCr 2 O 4 hybrid film [14] and polyglutamic acid/glutaraldehyde [12] modified glassy carbon electrodes (GCEs), nickel-curcumin complex [13] and polyaniline [15] modified carbon past electrodes and Au nanoparticles (NPs) modified indium tin oxide electrode [16]. However, their selectivity and/or sensitivity need to be further enhanced.…”

An Electrochemical Sensing Platform Based on Graphene Oxide and Molecularly Imprinted Polymer Modified Electrode for Selective Detection of Amoxicillin

“…Table 1 reveals that the designed sensor exhibited high selectivity, low detection limit and wide linear range compare to non‐MIP voltammetric sensors for electrochemical detection of AMOX [6, 17, 20, 21, 55]. The study reported by Chowdhury et al ., which is based on the gold nanoparticle modified indium tin oxide (ITO/GNP) electrode for highly sensitive AMOX determination, showed low detection limit and wide linear range [18]. However, ITO/GNP sensor was not tested when AMOX and similar compounds coexisted, indicating the lack of selectivity for determination of AMOX .…”

“…Furthermore, since the solubility of AMOX in organic solvents is low, it is difficult to evolve extraction and pre‐concentration steps based procedures for HPLC. Besides this, the electrochemical methods offer an easier and cheaper way for determination of AMOX [17–21]. The main drawback for electrochemical methods is the high over‐potential of AMOX during its electro‐oxidation process and ill‐defined peak response with conventional electrodes.…”

Hydrogen Peroxide Biosensor based on the Immobilization of Horseradish Peroxidase onto a Gold Nanoparticles-Adsorbed Poly(brilliant cresyl blue) Film

“…29 Moreover, they have been used as a base materials for the immobilization of HRP and provides an environment similar to the native environment of enzyme. 30 Liu et al immobilized HRP onto GNPs, which was supported by poly(amidoamine) dendrimer/cystamine modified gold electrode.…”