Highly selective N-Alkylation of amines promoted on silica: An efficient and recyclable surface

Oxidative DNA cleavage by Cu(II) complexes: Effect of periphery substituent groups

“…Ligands, L 2 , L 3 , and L 5 , were synthesized as previously reported [36][37][38], whereas L 1 and L 4 were obtained by coupling of 2-picolyl chloride hydrochloride and two equimolar amounts of (4-methoxyphenyl)methanamine or 4-fluoro-benzylamine, respectively, in a mixture of water and acetonitrile (1/1) (Fig. 1).…”

Synthesis and Herbicidal Activity ofN-Acyl-N-(m-fluoro-benzyl)-6-amino-coumarin

“…间氟氯苄价 廉, 但与 b 直接缩合 [19] 易生成二取代副产物, 反应溶剂 及缚酸剂不好选择; 间氟苯甲醛较贵, 但以其制备 c1 [17,20] , 选择性高, 产率尚好. 合物除草活性不明显).…”

Iron-Catalyzed Tandem Reactions of ortho-Aminobenzenethiols with Isothiocyanates Leading to 2-Aminobenzoazoles Under Ligand- and Solvent-Free Conditions

“…14 Basu et al reported silica-promoted acylation and alkylation of aromatic and aliphatic thiols 15 and highly selective N-alkylation of amines. 16 In continuation of our work on transition metal-catalyzed tandem annulations for heterocyclic compounds, [18][19][20][21][22][23] we now report a new solid phase synthetic method, which could be used for generation of 2-aminobenzothiazole libraries. In this article, we describe a practical approach to 2-aminobenzothiazole based on parallel diversity-oriented synthesis catalyzed by Fe 2 (SO 4 ) 3 · H 2 O under ligand-free conditions on a silica gel surface.…”