Abstract:The increase in the use of electro spray ionization mass spectrometry (ESI MS) and matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) in the biomedical sciences has fueled an intense interest in analyzing smaller and smaller amounts of sample. Increases in sensitivity have allowed the analysis of samples in the low femtomole to subattomole range. This has been accomplished primarily by changes in the capillary size fsr ESI MS and in sample deposition methods for MALDI MS.
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.