High pressure liquid chromatographic determination of bergenin and (+) -afzelechin from different parts of Paashaanbhed (Bergenia ligulata yeo)

Major bioactive phenolics in Bergenia species from the Indian Himalayan region: Method development, validation and quantitative estimation using UHPLC-QqQLIT-MS/MS

“…The previously reported LOD and LOQ values for these phenolics ranged from 0.04 to 10.7 μg/mL by HPLC and HPTLC methods. However, in the present study the LOD and LOQ values for all analytes are ≤ 2.36 ng/mL, thus showing higher sensitivity than the earlier reports [ 8 , 19 , 21 , 23 – 24 , 27 – 28 , 39 ].…”

Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor

“…All the identified compounds based on HRMS data were further verified with the literature report i.e. Arbutin, Gallic Acid, Protocatechuic Acid, Bergenin, Catechin and Syringic Acid [39], Hyperoside [77], Afzelechin [78,79], Methyl Gallate [80], Paashaanolactone [81], Astilbin [82], Quercetin [83], Kaempferol-7-O-glucoside [84,85], Diosmetin [86], Phloretin [87], and Morin [88]. We firmly believe that presence of phenolic and flavonoids molecules are largely responsible for the bioactivities of B. pacumbis.…”

Transformation of Litchi Pericarp-Derived Condensed Tannin with Aspergillus awamori

“…These results were somewhat different from the previous studies [ 28 , 29 ], possibly due to the different litchi cultivar used. Epi/afzelechin is a flavan-3-ol, which exhibits significant anti-inflammatory, analgesic and diuretic properties [ 30 ]. The ‘Huaizhi’ litchi employed in this study is the widest planted cultivar in south China.…”