Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.11.027 View full text
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László Sipos, István Ilisz, Melinda Nonn, Ferenc Fülöp, Zoltán Pataj, Daniel W. Armstrong, Antal Péter

Abstract: The enantiomers of four unusual isoxazoline-fused 2-aminocyclopentanecarboxylic acids were directly separated on chiral stationary phases containing macrocyclic glycopeptide antibiotics teicoplanin (Astec Chirobiotic T and T2), teicoplanin aglycone (Chirobiotic TAG), vancomycin (Chirobiotic V) and vancomycin aglycone (Chirobiotic VAG) as chiral selectors. The effects of the mobile phase composition, the structure of the analytes and temperature on the separations were investigated. Experiments were performed a…

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