Abstract:Background. Mouse strains differ in body and skeletal muscle mass. It is commonly believed that specific force is a constant value irrespective of muscle mass. We hypothesised that excessive muscle hypertrophy might compromise force output.Methods. We studied force generating capacity and muscle mass of isolated soleus (SOL) and extensor digitorum longus (EDL) muscles in 14-15-week-old males of C57BL/6J, BEH+/+ and DUH mice (n = 7 per strain). In addition, muscles of young (4-5 weeks old, n = 7 per strain) BEH… Show more
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