2010
DOI: 10.3171/2009.6.spine08910
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Abstract: ObjectThe goal in this study was to review a series of patients who underwent surgical removal of intramedullary high-grade gliomas, focusing on the functional outcome, recurrence rates, and technical problems continually debated in neurosurgical practice.MethodsBetween December 1976 and December 2006, 22 patients underwent removal of intramedullary high-grade gliomas. Lesions were located in the cervical … Show more

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Cited by 76 publications
(65 citation statements)
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“…It has been observed that tumors located in the thoracic region may have a more favorable prognosis than those in the cervical region [7]. This is likely due to the increased morbidity associated with tumor invasion into the high cervical spinal cord, as well as cervical instability that may result from the resection of these tumors [7].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…It has been observed that tumors located in the thoracic region may have a more favorable prognosis than those in the cervical region [7]. This is likely due to the increased morbidity associated with tumor invasion into the high cervical spinal cord, as well as cervical instability that may result from the resection of these tumors [7].…”
Section: Discussionmentioning
confidence: 99%
“…It has been observed that tumors located in the thoracic region may have a more favorable prognosis than those in the cervical region [7]. This is likely due to the increased morbidity associated with tumor invasion into the high cervical spinal cord, as well as cervical instability that may result from the resection of these tumors [7]. Although the numbers were too low to establish statistical significance, patients with tumors in the cervical region survived an average of 12.5 months, those with thoracic tumors, an average of 18.7 months, and the one with a cervicothoracic tumor, 11.5 months.…”
Section: Discussionmentioning
confidence: 99%
“…Of these, spinal cord glioblastoma multiforme (GBM) is rare, representing approximately 7.5% of all spinal cord gliomas. [46121418202223] Treatment for spinal gliomas typically includes surgery with postoperative radiation and chemotherapy. In cases of spinal GBM, however, the prognosis is poor, with an average survival of 18 months.…”
Section: Introductionmentioning
confidence: 99%
“…Mean survival is quoted at 6 -19 months for grade III and IV spinal cord gliomas. Therefore these tumours are probably just as lethal as their brain counterparts (Cohen et al, 1989;McGirt et al, 2008;Raco et al, 2010). Treatment is the same with debulking, radiotherapy and temozolomide, but often an extensive debulking as with brain GBM is not possible, and the maximum amount of targeted radiotherapy is also less than with brain GBM.…”
Section: Spinal Cord Gliomasmentioning
confidence: 99%