Archives of Dermatology
 1995
DOI: 10.1001/archderm.131.5.574
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High-dose recombinant interleukin-2 in advanced cutaneous T-cell lymphoma

JP Marolleau1
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Cited by 19 publications

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“…Skin is one of the most common sites affected by GVHD; therefore, tumor cells in the skin could become an efficient target of the GVT effect. The efficacy of immunomodulatory therapies for MF and SS, such as systemic cytokines, fusion toxins and extracorporeal photopheresis, suggests that this disease can be controlled by an immunological mechanism [24,25,26]. Tumor cells of MF and SS have been shown to express specific human leukocyte antigen class I peptides recognized by cytotoxic T lymphocytes [27, 28].…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Skin is one of the most common sites affected by GVHD; therefore, tumor cells in the skin could become an efficient target of the GVT effect. The efficacy of immunomodulatory therapies for MF and SS, such as systemic cytokines, fusion toxins and extracorporeal photopheresis, suggests that this disease can be controlled by an immunological mechanism [24,25,26]. Tumor cells of MF and SS have been shown to express specific human leukocyte antigen class I peptides recognized by cytotoxic T lymphocytes [27, 28].…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…[4][5][6] The role of conventional ASCT has been hypothesized considering: (1) the anti-MF activity through immune mechanisms observed in phase I/II trials using systemic cytokines or fusion toxins; 14,15 (2) the skin as a target of both MF and GVHD, which one associates with the GVT effect. In addition, there has been evidence of a long-lasting CR and GVT effect after conventional ASCT in a few patients with advanced MF or Se´zary syndrome.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…A number of systemic cytokines such as interferon gamma, interleukin-2 and interleukin-12 act through immune mechanisms and have been reported to have anti-MF activity. [13][14][15][16][17] To our knowledge, this is the first reported evidence for an allogeneic graft-versus-mycosis fungoides effect.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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