Abstract:Mantle cell lymphoma (MCL) mainly affects elderly and long term response to standard chemotherapy is deceiving. The addition of Rituximab or high dose chemotherapy regimens may improve these results, but have not been evaluated in elderly patients or those with significant comorbidities. We thought to evaluate the safety and efficacy of a High dose Aracytine (Cytosine arabinoside), Rituximab and Dexamethasone (HARD) chemotherapy regimen in elderly patient with aggressive mantle cell lymphoma.
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